ENSGALG00000042045


Gallus gallus

Features
Gene ID: ENSGALG00000042045
  
Biological name :IRX3
  
Synonyms : iroquois homeobox 3 / IRX3
  
Possible biological names infered from orthology : Iroquois-class homeodomain protein IRX-3 / P78415 / P81067
  
Species: Gallus gallus
  
Chr. number: 11
Strand: 1
Band:
Gene start: 4648344
Gene end: 4649811
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000047311
NCBI entrez gene - 107054273     See in Manteia.
RefSeq - XM_015292372
swissprot - A0A1D5P3Q6
Ensembl - ENSGALG00000042045
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 irx3aENSDARG00000101076Danio rerio
 irx3bENSDARG00000031138Danio rerio
 IRX3ENSG00000177508Homo sapiens
 Irx3ENSMUSG00000031734Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IRX1 / iroquois-class homeodomain protein IRX-1 / P78414* / P81068* / iroquois homeobox 1*ENSGALG0000003099138
IRX4 / Q9YGS0 / Iroquois-class homeodomain protein IRX-4 / P78413* / Q9QY61* / iroquois homeobox 4*ENSGALG0000002289632
IRX2 / iroquois homeobox 2 / P81066* / Q9BZI1* / Iroquois-class homeodomain protein IRX-2 *ENSGALG0000001319331
IRX5 / iroquois homeobox 5 / P78411* / Q9JKQ4* / Iroquois-class homeodomain protein IRX-5 *ENSGALG0000000358824
IRX6 / iroquois homeobox 6 / P78412* / Q9ER75* / Iroquois-class homeodomain protein IRX-6 *ENSGALG0000002373824
MKX / mohawk homeobox / Q8IYA7*ENSGALG0000000742616


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003893  Iroquois-class homeodomain protein
 IPR003980  Histamine H3 receptor
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001505 regulation of neurotransmitter levels IEA
 biological_processGO:0001656 metanephros development IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007498 mesoderm development IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IEA
 biological_processGO:0072047 proximal/distal pattern formation involved in nephron development IEA
 biological_processGO:0072086 specification of loop of Henle identity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0004969 histamine receptor activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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