ENSDARG00000035648


Danio rerio

Features
Gene ID: ENSDARG00000035648
  
Biological name :irx4a
  
Synonyms : iroquois homeobox 4a / irx4a
  
Possible biological names infered from orthology : Iroquois-class homeodomain protein IRX-4 / iroquois homeobox 4 / IRX4 / P78413 / Q9QY61
  
Species: Danio rerio
  
Chr. number: 16
Strand: -1
Band:
Gene start: 378766
Gene end: 383664
  
Corresponding Affymetrix probe sets: Dr.25775.1.S1_at (Zebrafish Array)   NM_205698_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000051692
NCBI entrez gene - 402999     See in Manteia.
RefSeq - XM_021466666
RefSeq - NM_205698
RefSeq Peptide - NP_991261
swissprot - Q6NZU4
ZFIN ID - ZDB-GENE-040426-1825
Ensembl - ENSDARG00000035648
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IRX4ENSGALG00000022896Gallus gallus
 IRX4ENSG00000113430Homo sapiens
 Irx4ENSMUSG00000021604Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
irx4b / iroquois homeobox 4b / IRX4* / P78413* / Q9QY61* / iroquois homeobox 4* / Iroquois-class homeodomain protein IRX-4 *ENSDARG0000003605147
irx6a / iroquois homeobox 6a / IRX6* / P78412* / Q9ER75* / iroquois homeobox 6* / Iroquois-class homeodomain protein IRX-6 *ENSDARG0000003442038
irx3a / iroquois homeobox 3a / IRX3* / P78415* / P81067* / iroquois homeobox 3* / Iroquois-class homeodomain protein IRX-3 *ENSDARG0000010107630
irx1b / iroquois homeobox 1bENSDARG0000005659429
irx5a / iroquois homeobox 5a / IRX5* / P78411* / Q9JKQ4* / iroquois homeobox 5* / Iroquois-class homeodomain protein IRX-5 *ENSDARG0000003404329
irx1a / iroquois homeobox 1a / IRX1* / P78414* / iroquois homeobox 1*ENSDARG0000010183129
irx2a / iroquois homeobox 2a / IRX2* / P81066* / Q9BZI1* / iroquois homeobox 2* / Iroquois-class homeodomain protein IRX-2 *ENSDARG0000000178529
irx3b / iroquois homeobox 3b / IRX3* / P78415* / iroquois homeobox 3*ENSDARG0000003113828
irx5b / iroquois homeobox 5b / IRX5* / P78411* / Q9JKQ4* / iroquois homeobox 5* / Iroquois-class homeodomain protein IRX-5 *ENSDARG0000007407026
irx7 / iroquois homeobox 7ENSDARG0000000260123
mkxa / mohawk homeobox a / MKX* / Q8IYA7* / mohawk homeobox*ENSDARG0000007545018
mkxb / mohawk homeobox b / MKX* / Q8IYA7* / mohawk homeobox*ENSDARG0000011418215


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003893  Iroquois-class homeodomain protein
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0042461 photoreceptor cell development IMP
 biological_processGO:0048923 posterior lateral line neuromast hair cell differentiation IMP
 biological_processGO:0048924 posterior lateral line neuromast mantle cell differentiation IMP
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 ZFA:0000008 brain brain decreased size , abnormal
Show

 ZFA:0000054 pericardium pericardium edematous , abnormal
Show

 ZFA:0000107 eye eye decreased size , abnormal
Show

 ZFA:0000295 trigeminal ganglion trigeminal ganglion neuron decreased amount , abnormal
Show

 ZFA:0001094 whole organism whole organism dead , abnormal
Show

 ZFA:0001718 presumptive atrium heart tube presumptive atrium heart tube increased size , abnormal
Show

 ZFA:0001719 presumptive cardiac ventricle heart tube presumptive cardiac ventricle heart tube decreased size , abnormal
Show

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr