ENSG00000159387


Homo sapiens

Features
Gene ID: ENSG00000159387
  
Biological name :IRX6
  
Synonyms : iroquois homeobox 6 / IRX6 / P78412
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q12.2
Gene start: 55323760
Gene end: 55330760
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000290552
NCBI entrez gene - 79190     See in Manteia.
OMIM - 606196
RefSeq - NM_024335
RefSeq - XM_005256137
RefSeq Peptide - NP_077311
swissprot - P78412
Ensembl - ENSG00000159387
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 irx6aENSDARG00000034420Danio rerio
 IRX6ENSGALG00000023738Gallus gallus
 Irx6ENSMUSG00000031738Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IRX4 / P78413 / iroquois homeobox 4ENSG0000011343041
IRX1 / P78414 / iroquois homeobox 1ENSG0000017054934
IRX3 / P78415 / iroquois homeobox 3ENSG0000017750832
IRX5 / P78411 / iroquois homeobox 5ENSG0000017684231
IRX2 / Q9BZI1 / iroquois homeobox 2ENSG0000017056129
MKX / Q8IYA7 / mohawk homeoboxENSG0000015005118


Protein motifs (from Interpro)
Interpro ID Name
 IPR001356  Homeobox domain
 IPR003893  Iroquois-class homeodomain protein
 IPR008422  Homeobox KN domain
 IPR009057  Homeobox-like domain superfamily
 IPR017970  Homeobox, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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