ENSG00000157368


Homo sapiens

Features
Gene ID: ENSG00000157368
  
Biological name :IL34
  
Synonyms : IL34 / interleukin 34 / Q6ZMJ4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: q22.1
Gene start: 70579895
Gene end: 70660682
  
Corresponding Affymetrix probe sets: 237046_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000463886
Ensembl peptide - ENSP00000288098
Ensembl peptide - ENSP00000397863
Ensembl peptide - ENSP00000455240
NCBI entrez gene - 146433     See in Manteia.
OMIM - 612081
RefSeq - XM_011522903
RefSeq - NM_001172771
RefSeq - NM_001172772
RefSeq - NM_152456
RefSeq - XM_011522902
RefSeq Peptide - NP_001166243
RefSeq Peptide - NP_689669
RefSeq Peptide - NP_001166242
swissprot - Q6ZMJ4
swissprot - H3BPB7
swissprot - A0A024QZ87
swissprot - J3QQT3
Ensembl - ENSG00000157368
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 il34ENSDARG00000091003Danio rerio
 IL34ENSGALG00000028466Gallus gallus
 Il34ENSMUSG00000031750Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR020415  Interleukin-34


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IDA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0008284 positive regulation of cell proliferation IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045651 positive regulation of macrophage differentiation IDA
 biological_processGO:0045657 positive regulation of monocyte differentiation IDA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005157 macrophage colony-stimulating factor receptor binding IDA
 molecular_functionGO:0008083 growth factor activity IEA


Pathways (from Reactome)
Pathway description
Other interleukin signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000115884 SDC1 / P18827 / syndecan 1  / reaction / complex
 ENSG00000184371 CSF1 / P09603 / colony stimulating factor 1  / reaction / complex
 ENSG00000157368 IL34 / Q6ZMJ4 / interleukin 34  / reaction / complex
 ENSG00000106278 P23471 / PTPRZ1 / protein tyrosine phosphatase, receptor type Z1  / complex / reaction
 ENSG00000182578 CSF1R / P07333 / colony stimulating factor 1 receptor  / reaction / complex






 

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