ENSG00000158106


Homo sapiens

Features
Gene ID: ENSG00000158106
  
Biological name :RHPN1
  
Synonyms : Q8TCX5 / rhophilin Rho GTPase binding protein 1 / RHPN1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q24.3
Gene start: 143368887
Gene end: 143384220
  
Corresponding Affymetrix probe sets: 228405_at (Human Genome U133 Plus 2.0 Array)   235998_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000289013
NCBI entrez gene - 114822     See in Manteia.
OMIM - 601031
RefSeq - XM_017013016
RefSeq - NM_052924
RefSeq - XM_017013014
RefSeq - XM_017013015
RefSeq - XM_005250772
RefSeq - XM_005250773
RefSeq - XM_006716502
RefSeq - XM_011516817
RefSeq - XM_011516818
RefSeq - XM_011516819
RefSeq - XM_011516820
RefSeq - XM_011516821
RefSeq - XM_011516822
RefSeq - XM_011516823
RefSeq - XM_017013013
RefSeq Peptide - NP_443156
swissprot - Q8TCX5
Ensembl - ENSG00000158106
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rhpn1ENSDARG00000052454Danio rerio
 RHPN1ENSGALG00000034337Gallus gallus
 Rhpn1ENSMUSG00000022580Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RHPN2 / Q8IUC4 / rhophilin Rho GTPase binding protein 2ENSG0000013194141
PTPN23 / Q9H3S7 / protein tyrosine phosphatase, non-receptor type 23ENSG0000007620121
Q8WUM4 / PDCD6IP / programmed cell death 6 interacting proteinENSG0000017024817


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR004328  BRO1 domain
 IPR011072  HR1 rho-binding domain
 IPR036034  PDZ superfamily
 IPR036274  HR1 repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Rhotekin and Rhophilins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000067560 RHOA / P61586 / ras homolog family member A  / complex / reaction
 ENSG00000065371 ROPN1 / Q9HAT0 / rhophilin associated tail protein 1  / complex / reaction






 

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