ENSG00000170248


Homo sapiens

Features
Gene ID: ENSG00000170248
  
Biological name :PDCD6IP
  
Synonyms : PDCD6IP / programmed cell death 6 interacting protein / Q8WUM4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: p22.3
Gene start: 33798352
Gene end: 33869707
  
Corresponding Affymetrix probe sets: 217746_s_at (Human Genome U133 Plus 2.0 Array)   222394_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000411825
Ensembl peptide - ENSP00000406693
Ensembl peptide - ENSP00000415150
Ensembl peptide - ENSP00000307387
Ensembl peptide - ENSP00000393777
Ensembl peptide - ENSP00000398895
NCBI entrez gene - 10015     See in Manteia.
OMIM - 608074
RefSeq - XM_017005488
RefSeq - NM_001162429
RefSeq - NM_013374
RefSeq - XM_011533252
RefSeq - XM_011533253
RefSeq Peptide - NP_001155901
RefSeq Peptide - NP_037506
swissprot - F8WDK9
swissprot - F8WEQ7
swissprot - Q8WUM4
swissprot - F8WBR8
swissprot - C9IZF9
Ensembl - ENSG00000170248
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pdcd6ipENSDARG00000025269Danio rerio
 PDCD6IPENSGALG00000033500Gallus gallus
 Q9WU78ENSMUSG00000032504Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PTPN23 / Q9H3S7 / protein tyrosine phosphatase, non-receptor type 23ENSG0000007620126
RHPN1 / Q8TCX5 / rhophilin Rho GTPase binding protein 1ENSG0000015810613
RHPN2 / Q8IUC4 / rhophilin Rho GTPase binding protein 2ENSG0000013194112


Protein motifs (from Interpro)
Interpro ID Name
 IPR004328  BRO1 domain
 IPR025304  ALIX V-shaped domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000281 mitotic cytokinesis IDA
 biological_processGO:0000915 actomyosin contractile ring assembly IEA
 biological_processGO:0000920 cell separation after cytokinesis IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010824 regulation of centrosome duplication IMP
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0019058 viral life cycle TAS
 biological_processGO:0036258 multivesicular body assembly NAS
 biological_processGO:0039702 viral budding via host ESCRT complex IGI
 biological_processGO:0045199 maintenance of epithelial cell apical/basal polarity IEA
 biological_processGO:0046755 viral budding IDA
 biological_processGO:0051260 protein homooligomerization IDA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0070830 bicellular tight junction assembly IEA
 biological_processGO:0090559 regulation of membrane permeability IEA
 biological_processGO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway IMP
 biological_processGO:1903543 positive regulation of exosomal secretion IMP
 biological_processGO:1903551 regulation of extracellular exosome assembly IMP
 biological_processGO:1903553 positive regulation of extracellular exosome assembly IMP
 cellular_componentGO:0001772 immunological synapse IDA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0042641 actomyosin IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0070062 extracellular exosome IEA
 cellular_componentGO:0070971 endoplasmic reticulum exit site IMP
 cellular_componentGO:0090543 Flemming body IEA
 cellular_componentGO:1903561 extracellular vesicle HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031871 proteinase activated receptor binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0046983 protein dimerization activity IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IPI


Pathways (from Reactome)
Pathway description
Budding and maturation of HIV virion
Uptake and function of anthrax toxins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr