ENSG00000131941


Homo sapiens

Features
Gene ID: ENSG00000131941
  
Biological name :RHPN2
  
Synonyms : Q8IUC4 / rhophilin Rho GTPase binding protein 2 / RHPN2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: q13.11
Gene start: 32978593
Gene end: 33064888
  
Corresponding Affymetrix probe sets: 227196_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000254260
Ensembl peptide - ENSP00000465898
NCBI entrez gene - 85415     See in Manteia.
RefSeq - NM_033103
RefSeq Peptide - NP_149094
swissprot - K7EL35
swissprot - Q8IUC4
Ensembl - ENSG00000131941
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rhpn2ENSDARG00000014577Danio rerio
 RHPN2ENSGALG00000004814Gallus gallus
 Rhpn2ENSMUSG00000030494Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
RHPN1 / Q8TCX5 / rhophilin Rho GTPase binding protein 1ENSG0000015810640
PTPN23 / Q9H3S7 / protein tyrosine phosphatase, non-receptor type 23ENSG0000007620118
Q8WUM4 / PDCD6IP / programmed cell death 6 interacting proteinENSG0000017024816


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR004328  BRO1 domain
 IPR011072  HR1 rho-binding domain
 IPR036034  PDZ superfamily
 IPR036274  HR1 repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Rhotekin and Rhophilins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000067560 RHOA / P61586 / ras homolog family member A  / reaction / complex
 ENSG00000143878 RHOB / P62745 / ras homolog family member B  / reaction / complex






 

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contact: otassy@igbmc.fr