ENSMUSG00000030494


Mus musculus

Features
Gene ID: ENSMUSG00000030494
  
Biological name :Rhpn2
  
Synonyms : Q8BWR8 / Rhophilin-2 / Rhpn2
  
Possible biological names infered from orthology : Q8IUC4 / rhophilin Rho GTPase binding protein 2
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: B2
Gene start: 35334170
Gene end: 35392289
  
Corresponding Affymetrix probe sets: 10552156 (MoGene1.0st)   1431805_a_at (Mouse Genome 430 2.0 Array)   1434628_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000032705
Ensembl peptide - ENSMUSP00000082692
NCBI entrez gene - 52428     See in Manteia.
MGI - MGI:1289234
RefSeq - NM_027897
RefSeq Peptide - NP_082173
swissprot - Q8BWR8
Ensembl - ENSMUSG00000030494
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rhpn2ENSDARG00000014577Danio rerio
 RHPN2ENSGALG00000004814Gallus gallus
 RHPN2ENSG00000131941Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Rhpn1 / Q61085 / Rhophilin-1 / Q8TCX5* / rhophilin Rho GTPase binding protein 1*ENSMUSG0000002258043
Ptpn23 / Q6PB44 / Tyrosine-protein phosphatase non-receptor type 23 / Q9H3S7* / protein tyrosine phosphatase, non-receptor type 23*ENSMUSG0000003605719
Q9WU78 / Pdcd6ip / Programmed cell death 6-interacting protein / Q8WUM4*ENSMUSG0000003250416


Protein motifs (from Interpro)
Interpro ID Name
 IPR001478  PDZ domain
 IPR004328  BRO1 domain
 IPR011072  HR1 rho-binding domain
 IPR036034  PDZ superfamily
 IPR036274  HR1 repeat superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
RHO GTPases Activate Rhotekin and Rhophilins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Drd2tm1Mok/Drd2tm1Mok
Genetic Background: involves: 129S/SvEv

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000007815 Rhoa / Q9QUI0 / ras homolog family member A / P61586*  / complex / reaction






 

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