ENSG00000162747


Homo sapiens

Features
Gene ID: ENSG00000162747
  
Biological name :FCGR3B
  
Synonyms : Fc fragment of IgG receptor IIIb / FCGR3B / O75015
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.3
Gene start: 161623196
Gene end: 161631963
  
Corresponding Affymetrix probe sets: 204006_s_at (Human Genome U133 Plus 2.0 Array)   204007_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000433642
Ensembl peptide - ENSP00000294800
Ensembl peptide - ENSP00000394204
Ensembl peptide - ENSP00000437084
Ensembl peptide - ENSP00000482838
Ensembl peptide - ENSP00000478466
Ensembl peptide - ENSP00000356941
NCBI entrez gene - 2215     See in Manteia.
OMIM - 610665
RefSeq - NM_001271037
RefSeq - NM_000570
RefSeq - NM_001244753
RefSeq - NM_001271035
RefSeq - NM_001271036
RefSeq Peptide - NP_000561
RefSeq Peptide - NP_001257966
RefSeq Peptide - NP_001257965
RefSeq Peptide - NP_001257964
RefSeq Peptide - NP_001231682
swissprot - O75015
swissprot - A0A087WU90
swissprot - A0A087WZR4
swissprot - E9PNY5
swissprot - H0Y4U3
swissprot - M9MML6
Ensembl - ENSG00000162747
  
Related genetic diseases (OMIM): 610665 - Neutropenia, alloimmune neonatal
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Fcgr4ENSMUSG00000059089Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FCGR3A / P08637 / Fc fragment of IgG receptor IIIaENSG0000020374797
FCGR2A / P12318 / Fc fragment of IgG receptor IIaENSG0000014322638
FCGR2B / P31994 / Fc fragment of IgG receptor IIbENSG0000007269437
FCGR2C / Fc fragment of IgG receptor IIc (gene/pseudogene)ENSG0000024468236
FCGR1A / P12314 / Fc fragment of IgG receptor IaENSG0000015033735
FCGR1B / Q92637 / Fc fragment of IgG receptor IbENSG0000019801933
FCER1A / P12319 / Fc fragment of IgE receptor IaENSG0000017963932
FCRLB / Q6BAA4 / Fc receptor like BENSG0000016274627
FCRL5 / Q96RD9 / Fc receptor like 5ENSG0000014329727
FCRL3 / Q96P31 / Fc receptor like 3ENSG0000016085622
FCRL4 / Q96PJ5 / Fc receptor like 4ENSG0000016351822
FCRLA / Q7L513 / Fc receptor like AENSG0000013218519
FCRL2 / Q96LA5 / Fc receptor like 2ENSG0000013270416
FCRL6 / Q6DN72 / Fc receptor like 6ENSG0000018103615
FCRL1 / Q96LA6 / Fc receptor like 1ENSG000001635344


Protein motifs (from Interpro)
Interpro ID Name
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0006955 immune response TAS
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030667 secretory granule membrane TAS
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0019864 IgG binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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