ENSG00000163283


Homo sapiens

Features
Gene ID: ENSG00000163283
  
Biological name :ALPP
  
Synonyms : alkaline phosphatase, placental / ALPP / P05187
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.1
Gene start: 232378534
Gene end: 232382889
  
Corresponding Affymetrix probe sets: 204664_at (Human Genome U133 Plus 2.0 Array)   211619_s_at (Human Genome U133 Plus 2.0 Array)   216377_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000375881
NCBI entrez gene - 250     See in Manteia.
OMIM - 171800
RefSeq - NM_001632
RefSeq Peptide - NP_001623
swissprot - P05187
Ensembl - ENSG00000163283
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 alp3ENSDARG00000098063Danio rerio
 alpi.1ENSDARG00000015273Danio rerio
 alpi.2ENSDARG00000053774Danio rerio
 ENSGALG00000007814Gallus gallus
 Akp3ENSMUSG00000036500Mus musculus
 AlpiENSMUSG00000079440Mus musculus
 Alppl2ENSMUSG00000026246Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ALPPL2 / P10696 / alkaline phosphatase, placental like 2ENSG0000016328695
ALPI / P09923 / alkaline phosphatase, intestinalENSG0000016329584
ALPL / P05186 / alkaline phosphatase, liver/bone/kidneyENSG0000016255152


Protein motifs (from Interpro)
Interpro ID Name
 IPR001952  Alkaline phosphatase
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR018299  Alkaline phosphatase, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0000287 magnesium ion binding ISS
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004035 alkaline phosphatase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding ISS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Intra-Golgi traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr