ENSG00000163286


Homo sapiens

Features
Gene ID: ENSG00000163286
  
Biological name :ALPPL2
  
Synonyms : alkaline phosphatase, placental like 2 / ALPPL2 / P10696
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.1
Gene start: 232406843
Gene end: 232410714
  
Corresponding Affymetrix probe sets: 210431_at (Human Genome U133 Plus 2.0 Array)   211619_s_at (Human Genome U133 Plus 2.0 Array)   216377_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000295453
NCBI entrez gene - 251     See in Manteia.
OMIM - 171810
RefSeq - NM_031313
RefSeq Peptide - NP_112603
swissprot - P10696
Ensembl - ENSG00000163286
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 alp3ENSDARG00000098063Danio rerio
 alpi.1ENSDARG00000015273Danio rerio
 alpi.2ENSDARG00000053774Danio rerio
 ENSGALG00000007814Gallus gallus
 Akp3ENSMUSG00000036500Mus musculus
 AlpiENSMUSG00000079440Mus musculus
 Alppl2ENSMUSG00000026246Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ALPP / P05187 / alkaline phosphatase, placentalENSG0000016328395
ALPI / P09923 / alkaline phosphatase, intestinalENSG0000016329586
ALPL / P05186 / alkaline phosphatase, liver/bone/kidneyENSG0000016255153


Protein motifs (from Interpro)
Interpro ID Name
 IPR001952  Alkaline phosphatase
 IPR017849  Alkaline phosphatase-like, alpha/beta/alpha
 IPR017850  Alkaline-phosphatase-like, core domain superfamily
 IPR018299  Alkaline phosphatase, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0016311 dephosphorylation IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004035 alkaline phosphatase activity NAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016791 phosphatase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000163286 ALPPL2 / P10696 / alkaline phosphatase, placental like 2  / complex






 

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