ENSG00000163735


Homo sapiens

Features
Gene ID: ENSG00000163735
  
Biological name :CXCL5
  
Synonyms : CXCL5 / C-X-C motif chemokine ligand 5 / P42830
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q13.3
Gene start: 73995642
Gene end: 73998779
  
Corresponding Affymetrix probe sets: 207852_at (Human Genome U133 Plus 2.0 Array)   214974_x_at (Human Genome U133 Plus 2.0 Array)   215101_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000296027
NCBI entrez gene - 6374     See in Manteia.
OMIM - 600324
RefSeq - NM_002994
RefSeq Peptide - NP_002985
swissprot - P42830
swissprot - Q6I9S7
Ensembl - ENSG00000163735
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cxcl19ENSDARG00000102776Danio rerio
 ENSGALG00000046160Gallus gallus
 Cxcl5ENSMUSG00000029371Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CXCL6 / P80162 / C-X-C motif chemokine ligand 6ENSG0000012487580
PPBP / P02775 / pro-platelet basic proteinENSG0000016373642
CXCL2 / P19875 / C-X-C motif chemokine ligand 2ENSG0000008104141
CXCL1 / P09341 / C-X-C motif chemokine ligand 1ENSG0000016373941
CXCL3 / P19876 / C-X-C motif chemokine ligand 3ENSG0000016373440
CXCL8 / P10145 / C-X-C motif chemokine ligand 8ENSG0000016942927


Protein motifs (from Interpro)
Interpro ID Name
 IPR001089  CXC chemokine
 IPR001811  Chemokine interleukin-8-like domain
 IPR018048  CXC chemokine, conserved site
 IPR033899  CXC Chemokine domain
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002446 neutrophil mediated immunity IBA
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006952 defense response IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis IBA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008009 chemokine activity TAS
 molecular_functionGO:0042802 identical protein binding IDA
 molecular_functionGO:0045236 CXCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
Chemokine receptors bind chemokines
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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