ENSG00000163875


Homo sapiens

Features
Gene ID: ENSG00000163875
  
Biological name :MEAF6
  
Synonyms : MEAF6 / MYST/Esa1 associated factor 6 / Q9HAF1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p34.3
Gene start: 37492575
Gene end: 37514774
  
Corresponding Affymetrix probe sets: 218165_at (Human Genome U133 Plus 2.0 Array)   228517_at (Human Genome U133 Plus 2.0 Array)   230293_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362166
Ensembl peptide - ENSP00000394966
Ensembl peptide - ENSP00000296214
Ensembl peptide - ENSP00000362164
Ensembl peptide - ENSP00000362165
NCBI entrez gene - 64769     See in Manteia.
OMIM - 611001
RefSeq - NM_001270875
RefSeq - NM_001270876
RefSeq - NM_022756
RefSeq Peptide - NP_073593
RefSeq Peptide - NP_001257804
RefSeq Peptide - NP_001257805
swissprot - Q9HAF1
swissprot - B1AK63
Ensembl - ENSG00000163875
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 meaf6ENSDARG00000101216Danio rerio
 MEAF6ENSGALG00000002013Gallus gallus
 Meaf6ENSMUSG00000028863Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR015418  Chromatin modification-related protein Eaf6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0043968 histone H2A acetylation IDA
 biological_processGO:0043981 histone H4-K5 acetylation IDA
 biological_processGO:0043982 histone H4-K8 acetylation IDA
 biological_processGO:0043983 histone H4-K12 acetylation IDA
 biological_processGO:0044154 histone H3-K14 acetylation IDA
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 cellular_componentGO:0000123 histone acetyltransferase complex IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex IDA
 cellular_componentGO:0070776 MOZ/MORF histone acetyltransferase complex IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
HATs acetylate histones
Regulation of TP53 Activity through Acetylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000136504 KAT7 / O95251 / lysine acetyltransferase 7  / complex
 ENSG00000083168 KAT6A / Q92794 / lysine acetyltransferase 6A  / complex
 ENSG00000156650 KAT6B / Q8WYB5 / lysine acetyltransferase 6B  / complex
 ENSG00000140464 PML / P29590 / promyelocytic leukemia  / reaction / complex
 ENSG00000275714 P68431 / HIST1H3A / histone cluster 1 H3 family member a  / reaction
 ENSG00000077684 JADE1 / Q6IE81 / jade family PHD finger 1  / complex
 ENSG00000156983 BRPF1 / P55201 / bromodomain and PHD finger containing 1  / complex
 ENSG00000141510 TP53 / P04637 / tumor protein p53  / complex / reaction
 ENSG00000168395 ING5 / Q8WYH8 / inhibitor of growth family member 5  / complex
 ENSG00000111653 ING4 / Q9UNL4 / inhibitor of growth family member 4  / complex
 ENSG00000142208 AKT1 / P31749 / AKT serine/threonine kinase 1  / reaction






 

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