ENSG00000163950


Homo sapiens

Features
Gene ID: ENSG00000163950
  
Biological name :SLBP
  
Synonyms : Q14493 / SLBP / stem-loop binding protein
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: p16.3
Gene start: 1692800
Gene end: 1712555
  
Corresponding Affymetrix probe sets: 206052_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418658
Ensembl peptide - ENSP00000406322
Ensembl peptide - ENSP00000316490
Ensembl peptide - ENSP00000417686
Ensembl peptide - ENSP00000426891
Ensembl peptide - ENSP00000417359
NCBI entrez gene - 7884     See in Manteia.
OMIM - 602422
RefSeq - NM_001306075
RefSeq - NM_001306074
RefSeq - NM_006527
RefSeq Peptide - NP_001293003
RefSeq Peptide - NP_006518
RefSeq Peptide - NP_001293004
swissprot - Q53XR2
swissprot - E7EUV9
swissprot - F8W8D3
swissprot - H0YAE8
swissprot - H7C4H8
swissprot - Q14493
Ensembl - ENSG00000163950
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slbpENSDARG00000100558Danio rerio
 SLBPENSGALG00000015712Gallus gallus
 SlbpENSMUSG00000004642Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026502  Histone RNA stem-loop-binding protein SLBP1/SLBP2
 IPR029344  Histone RNA hairpin-binding protein, RNA-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006369 termination of RNA polymerase II transcription TAS
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006398 mRNA 3"-end processing by stem-loop binding and cleavage IEA
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0008334 histone mRNA metabolic process TAS
 biological_processGO:0033260 nuclear DNA replication IMP
 biological_processGO:0044770 cell cycle phase transition IMP
 biological_processGO:0051028 mRNA transport IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0071204 histone pre-mRNA 3"end processing complex IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0071207 histone pre-mRNA stem-loop binding IEA
 molecular_functionGO:0071208 histone pre-mRNA DCP binding ISS


Pathways (from Reactome)
Pathway description
Cleavage of Growing Transcript in the Termination Region
Transport of the SLBP Dependant Mature mRNA
SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000142528 Q8WTR7 / ZNF473 / zinc finger protein 473  / reaction / complex
 ENSG00000162231 NXF1 / Q9UBU9 / nuclear RNA export factor 1  / complex / reaction
 ENSG00000151247 EIF4E / P06730 / eukaryotic translation initiation factor 4E  / complex / reaction
 ENSG00000114503 NCBP2 / P52298 / nuclear cap binding protein subunit 2  / complex / reaction
 ENSG00000136937 NCBP1 / Q09161 / nuclear cap binding protein subunit 1  / reaction / complex






 

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