ENSG00000162231


Homo sapiens

Features
Gene ID: ENSG00000162231
  
Biological name :NXF1
  
Synonyms : nuclear RNA export factor 1 / NXF1 / Q9UBU9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q12.3
Gene start: 62792123
Gene end: 62806302
  
Corresponding Affymetrix probe sets: 208922_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000432530
Ensembl peptide - ENSP00000477375
Ensembl peptide - ENSP00000453885
Ensembl peptide - ENSP00000437296
Ensembl peptide - ENSP00000436679
Ensembl peptide - ENSP00000435742
Ensembl peptide - ENSP00000434301
Ensembl peptide - ENSP00000294172
Ensembl peptide - ENSP00000431381
NCBI entrez gene - 10482     See in Manteia.
OMIM - 602647
RefSeq - NM_001081491
RefSeq - NM_006362
RefSeq Peptide - NP_001074960
RefSeq Peptide - NP_006353
swissprot - H0YDU0
swissprot - E9PQA4
swissprot - Q9UBU9
swissprot - E9PMV7
swissprot - E9PLA7
swissprot - E9PIN3
swissprot - B4E227
Ensembl - ENSG00000162231
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nxf1ENSDARG00000055076Danio rerio
 zgc:153681ENSDARG00000086017Danio rerio
 Nxf1ENSMUSG00000010097Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NXF2B / Q9GZY0 / nuclear RNA export factor 2BENSG0000026943757
NXF2 / Q9GZY0 / nuclear RNA export factor 2ENSG0000026940557
NXF3 / Q9H4D5 / nuclear RNA export factor 3ENSG0000014720644
NXF5 / Q9H1B4 / nuclear RNA export factor 5ENSG0000012695233


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR002075  Nuclear transport factor 2
 IPR005637  TAP C-terminal (TAP-C) domain
 IPR009060  UBA-like superfamily
 IPR015245  Nuclear RNA export factor Tap, RNA-binding domain
 IPR018222  Nuclear transport factor 2, eukaryote
 IPR030217  Nuclear RNA export factor
 IPR032675  Leucine-rich repeat domain superfamily
 IPR032710  NTF2-like domain superfamily
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016973 poly(A)+ mRNA export from nucleus IBA
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0000346 transcription export complex IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005643 nuclear pore IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0042405 nuclear inclusion body IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003729 mRNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Transport of the SLBP independent Mature mRNA
Transport of the SLBP Dependant Mature mRNA
Transport of Mature mRNA Derived from an Intronless Transcript
Transport of Mature mRNA derived from an Intron-Containing Transcript


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132661 NXT1 / Q9UKK6 / nuclear transport factor 2 like export factor 1  / complex
 ENSG00000163950 SLBP / Q14493 / stem-loop binding protein  / complex / reaction
 ENSG00000114503 NCBP2 / P52298 / nuclear cap binding protein subunit 2  / reaction
 ENSG00000136937 NCBP1 / Q09161 / nuclear cap binding protein subunit 1  / reaction
 ENSG00000151247 EIF4E / P06730 / eukaryotic translation initiation factor 4E  / reaction






 

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