ENSG00000269405


Homo sapiens

Features
Gene ID: ENSG00000269405
  
Biological name :NXF2
  
Synonyms : nuclear RNA export factor 2 / NXF2 / Q9GZY0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: q22.1
Gene start: 102247161
Gene end: 102326719
  
Corresponding Affymetrix probe sets: 220257_x_at (Human Genome U133 Plus 2.0 Array)   220981_x_at (Human Genome U133 Plus 2.0 Array)   234173_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000485586
Ensembl peptide - ENSP00000474598
NCBI entrez gene - 56001     See in Manteia.
OMIM - 300315
RefSeq - NM_022053
RefSeq Peptide - NP_071336
swissprot - Q9GZY0
Ensembl - ENSG00000269405
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nxf1ENSDARG00000055076Danio rerio
 zgc:153681ENSDARG00000086017Danio rerio
 Nxf2ENSMUSG00000009941Mus musculus
 Nxf7ENSMUSG00000031410Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NXF2B / Q9GZY0 / nuclear RNA export factor 2BENSG00000269437100
NXF1 / Q9UBU9 / nuclear RNA export factor 1ENSG0000016223156
NXF5 / Q9H1B4 / nuclear RNA export factor 5ENSG0000012695251
NXF3 / Q9H4D5 / nuclear RNA export factor 3ENSG0000014720645


Protein motifs (from Interpro)
Interpro ID Name
 IPR001611  Leucine-rich repeat
 IPR002075  Nuclear transport factor 2
 IPR005637  TAP C-terminal (TAP-C) domain
 IPR009060  UBA-like superfamily
 IPR015245  Nuclear RNA export factor Tap, RNA-binding domain
 IPR018222  Nuclear transport factor 2, eukaryote
 IPR030217  Nuclear RNA export factor
 IPR030218  Nuclear RNA export factor 5
 IPR032675  Leucine-rich repeat domain superfamily
 IPR032710  NTF2-like domain superfamily
 IPR035979  RNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006405 RNA export from nucleus TAS
 biological_processGO:0006406 mRNA export from nucleus TAS
 biological_processGO:0007275 multicellular organism development ISS
 biological_processGO:0016973 poly(A)+ mRNA export from nucleus IBA
 biological_processGO:0050658 RNA transport ISS
 biological_processGO:0051028 mRNA transport IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0042272 nuclear RNA export factor complex NAS
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132661 NXT1 / Q9UKK6 / nuclear transport factor 2 like export factor 1  / complex






 

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