ENSG00000164256


Homo sapiens

Features
Gene ID: ENSG00000164256
  
Biological name :PRDM9
  
Synonyms : PRDM9 / PR/SET domain 9 / Q9NQV7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: p14.2
Gene start: 23443586
Gene end: 23528597
  
Corresponding Affymetrix probe sets: 221151_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000296682
Ensembl peptide - ENSP00000489227
Ensembl peptide - ENSP00000425471
NCBI entrez gene - 56979     See in Manteia.
OMIM - 609760
RefSeq - NM_020227
RefSeq Peptide - NP_064612
swissprot - D6RD68
swissprot - A0A0U1RQY2
swissprot - Q9NQV7
Ensembl - ENSG00000164256
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Prdm9ENSMUSG00000051977Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HKR1 / P10072 / HKR1, GLI-Kruppel zinc finger family memberENSG0000018166633
P52736 / ZNF133 / zinc finger protein 133ENSG0000012584632
Q14929 / ZNF169 / zinc finger protein 169ENSG0000017578730
Q9Y3M9 / ZNF337 / zinc finger protein 337ENSG0000013068429
Q6P1L6 / ZNF343 / zinc finger protein 343ENSG0000008887621
Q86UQ0 / ZNF589 / zinc finger protein 589ENSG0000016404815


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR001909  Krueppel-associated box
 IPR003655  Krueppel-associated box-related
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013087  Zinc finger C2H2-type
 IPR019041  SSXRD motif
 IPR028804  SSX
 IPR036051  KRAB domain superfamily
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006311 meiotic gene conversion IDA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0010845 positive regulation of reciprocal meiotic recombination IMP
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity TAS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
PKMTs methylate histone lysines
Meiotic recombination


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000132475 H3F3B / P84243 / H3 histone family member 3B  / reaction
 ENSG00000275714 P68431 / HIST1H3A / histone cluster 1 H3 family member a  / reaction
 ENSG00000183598 Q71DI3 / HIST2H3D / histone cluster 2 H3 family member d  / reaction
 ENSG00000276180 P62805 / HIST1H4I / histone cluster 1 H4 family member i  / reaction






 

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