ENSG00000166148


Homo sapiens

Features
Gene ID: ENSG00000166148
  
Biological name :AVPR1A
  
Synonyms : arginine vasopressin receptor 1A / AVPR1A / P37288
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q14.2
Gene start: 63142759
Gene end: 63150942
  
Corresponding Affymetrix probe sets: 206250_x_at (Human Genome U133 Plus 2.0 Array)   206251_s_at (Human Genome U133 Plus 2.0 Array)   206252_s_at (Human Genome U133 Plus 2.0 Array)   238835_at (Human Genome U133 Plus 2.0 Array)   242680_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000299178
Ensembl peptide - ENSP00000449822
NCBI entrez gene - 552     See in Manteia.
OMIM - 600821
RefSeq - NM_000706
RefSeq Peptide - NP_000697
swissprot - X5D2B0
swissprot - F8VW98
swissprot - P37288
Ensembl - ENSG00000166148
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 avpr1aaENSDARG00000077083Danio rerio
 avpr1abENSDARG00000045788Danio rerio
 AVPR1AENSGALG00000040567Gallus gallus
 Avpr1aENSMUSG00000020123Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AVPR1B / P47901 / arginine vasopressin receptor 1BENSG0000019804947
OXTR / P30559 / oxytocin receptorENSG0000018091445
AVPR2 / P30518 / arginine vasopressin receptor 2ENSG0000012689533
NPSR1 / Q6W5P4 / neuropeptide S receptor 1ENSG0000018725824
GNRHR / P30968 / gonadotropin releasing hormone receptorENSG0000010916321
GPR19 / Q15760 / G protein-coupled receptor 19ENSG0000018315019


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001224  Vasopressin V1A receptor
 IPR001817  Vasopressin receptor
 IPR015076  Domain of unknown function DUF1856
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001992 regulation of systemic arterial blood pressure by vasopressin IEA
 biological_processGO:0002125 maternal aggressive behavior IEA
 biological_processGO:0003084 positive regulation of systemic arterial blood pressure IEA
 biological_processGO:0006091 generation of precursor metabolites and energy TAS
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007202 activation of phospholipase C activity TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 biological_processGO:0007621 negative regulation of female receptivity IEA
 biological_processGO:0007625 grooming behavior IEA
 biological_processGO:0008015 blood circulation TAS
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010033 response to organic substance IEA
 biological_processGO:0010035 response to inorganic substance IEA
 biological_processGO:0010460 positive regulation of heart rate IEA
 biological_processGO:0014049 positive regulation of glutamate secretion IEA
 biological_processGO:0014902 myotube differentiation IEA
 biological_processGO:0019722 calcium-mediated signaling IEA
 biological_processGO:0021537 telencephalon development IEA
 biological_processGO:0030307 positive regulation of cell growth IEA
 biological_processGO:0031394 positive regulation of prostaglandin biosynthetic process IEA
 biological_processGO:0032849 positive regulation of cellular pH reduction IEA
 biological_processGO:0032870 cellular response to hormone stimulus IBA
 biological_processGO:0035176 social behavior IEA
 biological_processGO:0035815 positive regulation of renal sodium excretion IEA
 biological_processGO:0042631 cellular response to water deprivation IEA
 biological_processGO:0042711 maternal behavior IEA
 biological_processGO:0042713 sperm ejaculation IEA
 biological_processGO:0043084 penile erection IEA
 biological_processGO:0045777 positive regulation of blood pressure IEA
 biological_processGO:0045907 positive regulation of vasoconstriction IEA
 biological_processGO:0051412 response to corticosterone IEA
 biological_processGO:0051970 negative regulation of transmission of nerve impulse IEA
 biological_processGO:1901652 response to peptide IBA
 cellular_componentGO:0005768 endosome TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005000 vasopressin receptor activity IEA
 molecular_functionGO:0005080 protein kinase C binding TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017046 peptide hormone binding IEA
 molecular_functionGO:0031894 V1A vasopressin receptor binding IEA
 molecular_functionGO:0042277 peptide binding IBA


Pathways (from Reactome)
Pathway description
Vasopressin-like receptors
G alpha (q) signalling events
Defective AVP causes neurohypophyseal diabetes insipidus (NDI)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101200 AVP / P01185 / arginine vasopressin  / complex / reaction






 

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