ENSG00000198049


Homo sapiens

Features
Gene ID: ENSG00000198049
  
Biological name :AVPR1B
  
Synonyms : arginine vasopressin receptor 1B / AVPR1B / P47901
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 206109692
Gene end: 206117699
  
Corresponding Affymetrix probe sets: 208260_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000356094
NCBI entrez gene - 553     See in Manteia.
OMIM - 600264
RefSeq - NM_000707
RefSeq Peptide - NP_000698
swissprot - P47901
Ensembl - ENSG00000198049
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AVPR1BENSGALG00000000788Gallus gallus
 Avpr1bENSMUSG00000026432Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AVPR1A / P37288 / arginine vasopressin receptor 1AENSG0000016614846
OXTR / P30559 / oxytocin receptorENSG0000018091446
AVPR2 / P30518 / arginine vasopressin receptor 2ENSG0000012689535
NPSR1 / Q6W5P4 / neuropeptide S receptor 1ENSG0000018725824
GNRHR / P30968 / gonadotropin releasing hormone receptorENSG0000010916319
GPR19 / Q15760 / G protein-coupled receptor 19ENSG0000018315018


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000628  Vasopressin V1B receptor
 IPR001817  Vasopressin receptor
 IPR015076  Domain of unknown function DUF1856
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001992 regulation of systemic arterial blood pressure by vasopressin IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007202 activation of phospholipase C activity TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration TAS
 biological_processGO:0032870 cellular response to hormone stimulus IBA
 biological_processGO:0045907 positive regulation of vasoconstriction IBA
 biological_processGO:1901652 response to peptide IBA
 cellular_componentGO:0005768 endosome TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005000 vasopressin receptor activity TAS
 molecular_functionGO:0005080 protein kinase C binding TAS
 molecular_functionGO:0042277 peptide binding IBA


Pathways (from Reactome)
Pathway description
Vasopressin-like receptors
G alpha (q) signalling events
Defective AVP causes neurohypophyseal diabetes insipidus (NDI)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000101200 AVP / P01185 / arginine vasopressin  / complex / reaction






 

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