ENSMUSG00000026432


Mus musculus

Features
Gene ID: ENSMUSG00000026432
  
Biological name :Avpr1b
  
Synonyms : Avpr1b / Q9WU02 / Vasopressin V1b receptor
  
Possible biological names infered from orthology : arginine vasopressin receptor 1B / P47901
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: E4
Gene start: 131599239
Gene end: 131612000
  
Corresponding Affymetrix probe sets: 10349644 (MoGene1.0st)   1422204_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000140527
Ensembl peptide - ENSMUSP00000027690
NCBI entrez gene - 26361     See in Manteia.
MGI - MGI:1347010
RefSeq - NM_011924
RefSeq Peptide - NP_036054
swissprot - A0A087WR95
swissprot - Q9WU02
Ensembl - ENSMUSG00000026432
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 AVPR1BENSGALG00000000788Gallus gallus
 AVPR1BENSG00000198049Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Avpr1a / Q62463 / arginine vasopressin receptor 1A / P37288*ENSMUSG0000002012347
Oxtr / P97926 / Oxytocin receptor / P30559*ENSMUSG0000004911246
Avpr2 / O88721 / arginine vasopressin receptor 2 / P30518*ENSMUSG0000003139036
Npsr1 / Q8BZP8 / Neuropeptide S receptor / Q6W5P4* / neuropeptide S receptor 1*ENSMUSG0000004365924
Gpr19 / Q61121 / Probable G-protein coupled receptor 19 / Q15760* / G protein-coupled receptor 19*ENSMUSG0000003264118
Gnrhr / Q01776 / gonadotropin releasing hormone receptor / P30968*ENSMUSG0000002925518


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000628  Vasopressin V1B receptor
 IPR001817  Vasopressin receptor
 IPR015076  Domain of unknown function DUF1856
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001992 regulation of systemic arterial blood pressure by vasopressin IGI
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0032870 cellular response to hormone stimulus IBA
 biological_processGO:0045907 positive regulation of vasoconstriction IBA
 biological_processGO:1901652 response to peptide IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005000 vasopressin receptor activity IEA
 molecular_functionGO:0042277 peptide binding IBA


Pathways (from Reactome)
Pathway description
Vasopressin-like receptors
G alpha (q) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001360 abnormal social investigation "altered behavior of animals to approach and examine other animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Erbb2tm7(Erbb2)Mul/Erbb2tm1Haus
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c

 MP:0002664 decreased circulating adrenocorticotropin level "decreased concentration in the blood of the pituitary hormone that stimulates the secretion of adrenal cortical steroids and induces growth of the adrenal cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002665 decreased circulating corticosterone level "less than the normal blood concentration of this adrenocortical steroid; induces glycogen deposition and regulates sodium conservation and potassium secretion" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002768 small adrenal glands "reduced size of endocrine glands located above the kidneys responsible for hormone and epinephrine secretion" [J:78062]
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Allelic Composition: Runx1tm2(Runx1)Toku/Runx1tm2(Runx1)Toku
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002781 increased circulating testosterone level "greater than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Erbb2tm7(Erbb2)Mul/Erbb2tm1Haus
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c

 MP:0002906 susceptibility to pharmacologically induced seizures "inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:69504]
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Allelic Composition: Selptm1Bay/Selptm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0005656 decreased aggression "when compared to controls, subjects exhibit less than the normal level of domineering, assaultive posture and/or hostile physical action" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator]
Show

Allelic Composition: Erbb2tm7(Erbb2)Mul/Erbb2tm1Haus
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000037727 Avp / P35455 / arginine vasopressin / P01185*  / reaction / complex






 

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