ENSMUSG00000043659


Mus musculus

Features
Gene ID: ENSMUSG00000043659
  
Biological name :Npsr1
  
Synonyms : Neuropeptide S receptor / Npsr1 / Q8BZP8
  
Possible biological names infered from orthology : neuropeptide S receptor 1 / Q6W5P4
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A3
Gene start: 24097996
Gene end: 24316398
  
Corresponding Affymetrix probe sets: 10583887 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000056432
Ensembl peptide - ENSMUSP00000117786
Ensembl peptide - ENSMUSP00000115126
NCBI entrez gene - 319239     See in Manteia.
MGI - MGI:2441738
RefSeq - XM_017313418
RefSeq - NM_175678
RefSeq - XM_017313417
RefSeq Peptide - NP_783609
swissprot - B1B1A4
swissprot - Q8BZP8
swissprot - A1KXK3
swissprot - A6X922
Ensembl - ENSMUSG00000043659
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NPSR1ENSGALG00000041820Gallus gallus
 NPSR1ENSG00000187258Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Avpr1b / Q9WU02 / Vasopressin V1b receptor / P47901* / arginine vasopressin receptor 1B*ENSMUSG0000002643228
Oxtr / P97926 / Oxytocin receptor / P30559*ENSMUSG0000004911227
Avpr1a / Q62463 / arginine vasopressin receptor 1A / P37288*ENSMUSG0000002012327
Avpr2 / O88721 / arginine vasopressin receptor 2 / P30518*ENSMUSG0000003139024
Gpr19 / Q61121 / Probable G-protein coupled receptor 19 / Q15760* / G protein-coupled receptor 19*ENSMUSG0000003264121
Gnrhr / Q01776 / gonadotropin releasing hormone receptor / P30968*ENSMUSG0000002925519


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001817  Vasopressin receptor
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR027294  Neuropeptide S receptor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005000 vasopressin receptor activity IEA
 molecular_functionGO:0008188 neuropeptide receptor activity IEA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0008872 abnormal response to xenobiotics "any anomaly in the physiological or morphological changes induced by a foreign compound, such as changes in blood pressure, changes in hormone or protein levels or hypertrophy or hypotrophy of an organ" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Tmiesr/Tmiesr
Genetic Background: C57BL/How-Tmiesr

 MP:0010936 decreased airway resistance "reduced opposition to flow of air caused by the forces of friction, measured as the ratio of driving pressure to the rate of air flow" [MGI:csmith]
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Allelic Composition: Tmiesr/Tmiesr
Genetic Background: C57BL/How-Tmiesr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000073804 Nps / P0C0P8 / Neuropeptide S / P0C0P6*  / complex / reaction






 

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