ENSG00000187258


Homo sapiens

Features
Gene ID: ENSG00000187258
  
Biological name :NPSR1
  
Synonyms : neuropeptide S receptor 1 / NPSR1 / Q6W5P4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p14.3
Gene start: 34658239
Gene end: 34878332
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000379402
Ensembl peptide - ENSP00000434955
Ensembl peptide - ENSP00000433258
Ensembl peptide - ENSP00000352839
Ensembl peptide - ENSP00000353788
Ensembl peptide - ENSP00000370950
Ensembl peptide - ENSP00000370953
Ensembl peptide - ENSP00000370955
Ensembl peptide - ENSP00000370965
NCBI entrez gene - 387129     See in Manteia.
OMIM - 608595
RefSeq - NM_207173
RefSeq - NM_001300933
RefSeq - NM_001300934
RefSeq - NM_001300935
RefSeq - NM_207172
RefSeq Peptide - NP_997055
RefSeq Peptide - NP_001287862
RefSeq Peptide - NP_001287863
RefSeq Peptide - NP_001287864
RefSeq Peptide - NP_997056
swissprot - Q6W5P4
swissprot - A0A090N8Z1
Ensembl - ENSG00000187258
  
Related genetic diseases (OMIM): 608584 - {Asthma, susceptibility to, 2}, 608584
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NPSR1ENSGALG00000041820Gallus gallus
 Npsr1ENSMUSG00000043659Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AVPR1A / P37288 / arginine vasopressin receptor 1AENSG0000016614826
AVPR1B / P47901 / arginine vasopressin receptor 1BENSG0000019804926
OXTR / P30559 / oxytocin receptorENSG0000018091425
AVPR2 / P30518 / arginine vasopressin receptor 2ENSG0000012689522
GNRHR / P30968 / gonadotropin releasing hormone receptorENSG0000010916319
GPR19 / Q15760 / G protein-coupled receptor 19ENSG0000018315019


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR001817  Vasopressin receptor
 IPR017452  GPCR, rhodopsin-like, 7TM
 IPR027294  Neuropeptide S receptor


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007218 neuropeptide signaling pathway IEA
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005000 vasopressin receptor activity IEA
 molecular_functionGO:0008188 neuropeptide receptor activity IDA


Pathways (from Reactome)
Pathway description
Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000214285 NPS / P0C0P6 / neuropeptide S  / complex / reaction






 

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