ENSG00000168702


Homo sapiens

Features
Gene ID: ENSG00000168702
  
Biological name :LRP1B
  
Synonyms : LDL receptor related protein 1B / LRP1B / Q9NZR2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q22.2
Gene start: 140231423
Gene end: 142131701
  
Corresponding Affymetrix probe sets: 219643_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000415052
Ensembl peptide - ENSP00000374135
Ensembl peptide - ENSP00000393859
Ensembl peptide - ENSP00000413239
NCBI entrez gene - 53353     See in Manteia.
OMIM - 608766
RefSeq - XM_017004342
RefSeq - NM_018557
RefSeq - XM_017004341
RefSeq Peptide - NP_061027
swissprot - E7ERG8
swissprot - Q9NZR2
swissprot - H0Y7T7
swissprot - H7C0A8
Ensembl - ENSG00000168702
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrp1baENSDARG00000004789Danio rerio
 lrp1bbENSDARG00000061517Danio rerio
 LRP1BENSGALG00000012407Gallus gallus
 Lrp1bENSMUSG00000049252Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRP1 / Q07954 / LDL receptor related protein 1ENSG0000012338460
LRP2 / P98164 / LDL receptor related protein 2ENSG0000008147934
LRP4 / O75096 / LDL receptor related protein 4ENSG0000013456914
LRP5 / O75197 / LDL receptor related protein 5ENSG0000016233711
LRP6 / O75581 / LDL receptor related protein 6ENSG0000007001811
LDLR / P01130 / low density lipoprotein receptorENSG000001301647
LRP8 / Q14114 / LDL receptor related protein 8ENSG000001571937
VLDLR / P98155 / very low density lipoprotein receptorENSG000001478527


Protein motifs (from Interpro)
Interpro ID Name
 IPR000033  LDLR class B repeat
 IPR000152  EGF-type aspartate/asparagine hydroxylation site
 IPR000742  EGF-like domain
 IPR001881  EGF-like calcium-binding domain
 IPR002172  Low-density lipoprotein (LDL) receptor class A repeat
 IPR009030  Growth factor receptor cysteine-rich domain superfamily
 IPR011042  Six-bladed beta-propeller, TolB-like
 IPR013032  EGF-like, conserved site
 IPR018097  EGF-like calcium-binding, conserved site
 IPR023415  Low-density lipoprotein (LDL) receptor class A, conserved site
 IPR026823  Complement Clr-like EGF domain
 IPR032485  Domain of unknown function DUF5050
 IPR036055  LDL receptor-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0006898 receptor-mediated endocytosis TAS
 biological_processGO:0015031 protein transport TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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