ENSG00000171236


Homo sapiens

Features
Gene ID: ENSG00000171236
  
Biological name :LRG1
  
Synonyms : leucine rich alpha-2-glycoprotein 1 / LRG1 / P02750
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 4536409
Gene end: 4540474
  
Corresponding Affymetrix probe sets: 228648_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000302621
NCBI entrez gene - 116844     See in Manteia.
OMIM - 611289
RefSeq - NM_052972
RefSeq Peptide - NP_443204
swissprot - P02750
Ensembl - ENSG00000171236
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-90m5.4ENSDARG00000029388Danio rerio
 LRG1ENSGALG00000027587Gallus gallus
 Lrg1ENSMUSG00000037095Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GP1BA / P07359 / glycoprotein Ib platelet alpha subunitENSG0000018524527
FLRT3 / Q9NZU0 / fibronectin leucine rich transmembrane protein 3ENSG0000012584824
FLRT1 / Q9NZU1 / fibronectin leucine rich transmembrane protein 1ENSG0000012650024
FLRT2 / O43155 / fibronectin leucine rich transmembrane protein 2ENSG0000018507021
OMG / P23515 / oligodendrocyte myelin glycoproteinENSG0000012686115


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001938 positive regulation of endothelial cell proliferation IEA
 biological_processGO:0008150 biological_process ND
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway IEA
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0050873 brown fat cell differentiation IEA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0016020 membrane NAS
 cellular_componentGO:0035580 specific granule lumen TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:1904724 tertiary granule lumen TAS
 cellular_componentGO:1904813 ficolin-1-rich granule lumen TAS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005160 transforming growth factor beta receptor binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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