ENSG00000126861


Homo sapiens

Features
Gene ID: ENSG00000126861
  
Biological name :OMG
  
Synonyms : oligodendrocyte myelin glycoprotein / OMG / P23515
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q11.2
Gene start: 31272013
Gene end: 31297539
  
Corresponding Affymetrix probe sets: 207093_s_at (Human Genome U133 Plus 2.0 Array)   238720_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000247271
NCBI entrez gene - 4974     See in Manteia.
OMIM - 164345
RefSeq - NM_002544
RefSeq Peptide - NP_002535
swissprot - P23515
Ensembl - ENSG00000126861
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 omgaENSDARG00000086573Danio rerio
 omgbENSDARG00000089444Danio rerio
 OMGENSGALG00000005594Gallus gallus
 OmgENSMUSG00000049612Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
FLRT1 / Q9NZU1 / fibronectin leucine rich transmembrane protein 1ENSG0000012650020
FLRT2 / O43155 / fibronectin leucine rich transmembrane protein 2ENSG0000018507019
GP1BA / P07359 / glycoprotein Ib platelet alpha subunitENSG0000018524517
FLRT3 / Q9NZU0 / fibronectin leucine rich transmembrane protein 3ENSG0000012584817
LRG1 / P02750 / leucine rich alpha-2-glycoprotein 1ENSG0000017123612


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007409 axonogenesis IBA
 biological_processGO:0050771 negative regulation of axonogenesis TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Axonal growth inhibition (RHOA activation)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000040608 RTN4R / Q9BZR6 / reticulon 4 receptor  / reaction / complex
 ENSG00000064300 NGFR / P08138 / nerve growth factor receptor  / reaction / complex
 ENSG00000141522 P52565 / ARHGDIA / Rho GDP dissociation inhibitor alpha  / complex / reaction
 ENSG00000067560 RHOA / P61586 / ras homolog family member A  / complex / reaction
 ENSG00000169783 LINGO1 / Q96FE5 / leucine rich repeat and Ig domain containing 1  / reaction / complex






 

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