ENSMUSG00000049612


Mus musculus

Features
Gene ID: ENSMUSG00000049612
  
Biological name :Omg
  
Synonyms : oligodendrocyte myelin glycoprotein / Omg
  
Possible biological names infered from orthology : P23515
  
Species: Mus musculus
  
Chr. number: 11
Strand: -1
Band: B5
Gene start: 79500982
Gene end: 79504084
  
Corresponding Affymetrix probe sets: 10388954 (MoGene1.0st)   1418212_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000132918
NCBI entrez gene - 18377     See in Manteia.
MGI - MGI:106586
RefSeq - NM_019409
RefSeq Peptide - NP_062282
swissprot - G3XA53
Ensembl - ENSMUSG00000049612
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 omgaENSDARG00000086573Danio rerio
 omgbENSDARG00000089444Danio rerio
 OMGENSGALG00000005594Gallus gallus
 OMGENSG00000126861Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Flrt1 / Q6RKD8 / Leucine-rich repeat transmembrane protein FLRT1 / Q9NZU1* / fibronectin leucine rich transmembrane protein 1*ENSMUSG0000004778720
Flrt2 / Q8BLU0 / Leucine-rich repeat transmembrane protein FLRT2 / O43155* / fibronectin leucine rich transmembrane protein 2*ENSMUSG0000004741419
Flrt3 / Q8BGT1 / Leucine-rich repeat transmembrane protein FLRT3 / Q9NZU0* / fibronectin leucine rich transmembrane protein 3*ENSMUSG0000005137918
Gp1ba / O35930 / glycoprotein 1b, alpha polypeptide / P07359* / glycoprotein Ib platelet alpha subunit*ENSMUSG0000005067518
Nepn / Q9CQ76 / Nephrocan ENSMUSG0000003862416
Lrg1 / leucine rich alpha-2-glycoprotein 1 / P02750*ENSMUSG0000003709512


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Axonal growth inhibition (RHOA activation)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lhx2tm1.1Ddmo/Lhx2tm1.1Ddmo,Tg(Nes-cre)1Kln/0
Genetic Background: involves: C57BL/6 * SJL

Allelic Composition: Omgtm1.3Bzh/Omgtm1.3Bzh
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * FVB/N * SJL

 MP:0005164 abnormal response to injury "anomaly in the body s reaction to trauma, especially that by physical means" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Shmt1tm1.1Stov/Shmt1tm1.1Stov
Genetic Background: 129S/SvEv-Shmt1tm1.1Stov

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000007815 Rhoa / Q9QUI0 / ras homolog family member A / P61586*  / reaction / complex
 ENSMUSG00000025132 Q99PT1 / Arhgdia / Rho GDP-dissociation inhibitor 1 / P52565* / Rho GDP dissociation inhibitor alpha*  / complex / reaction
 ENSMUSG00000043811 Rtn4r / Q99PI8 / Reticulon-4 receptor / Q9BZR6*  / complex / reaction
 ENSMUSG00000000120 Ngfr / nerve growth factor receptor / P08138*  / complex / reaction
 ENSMUSG00000049556 Lingo1 / Q9D1T0 / Leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein 1 / Q96FE5* / leucine rich repeat and Ig domain containing 1*  / complex / reaction






 

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