ENSG00000171940


Homo sapiens

Features
Gene ID: ENSG00000171940
  
Biological name :ZNF217
  
Synonyms : O75362 / zinc finger protein 217 / ZNF217
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.2
Gene start: 53567065
Gene end: 53609907
  
Corresponding Affymetrix probe sets: 203739_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000394010
Ensembl peptide - ENSP00000399672
Ensembl peptide - ENSP00000304308
Ensembl peptide - ENSP00000360526
NCBI entrez gene - 7764     See in Manteia.
OMIM - 602967
RefSeq - XM_005260545
RefSeq - XM_017028059
RefSeq - NM_006526
RefSeq Peptide - NP_006517
swissprot - O75362
swissprot - A2A326
swissprot - Q9BZ31
Ensembl - ENSG00000171940
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 znf217ENSDARG00000088123Danio rerio
 ENSGALG00000040546Gallus gallus
 Zfp217ENSMUSG00000052056Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
O15090 / ZNF536 / zinc finger protein 536ENSG0000019859726
Q92618 / ZNF516 / zinc finger protein 516ENSG0000010149324
Q9P2Y4 / ZNF219 / zinc finger protein 219ENSG0000016580414


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated TAS
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0000118 histone deacetylase complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0016607 nuclear speck IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000116833 NR5A2 / O00482 / nuclear receptor subfamily 5 group A member 2  / complex
 ENSG00000275714 P68431 / HIST1H3A / histone cluster 1 H3 family member a  / complex
 ENSG00000276180 P62805 / HIST1H4I / histone cluster 1 H4 family member i  / complex
 ENSG00000183598 Q71DI3 / HIST2H3D / histone cluster 2 H3 family member d  / complex
 ENSG00000091831 ESR1 / P03372 / estrogen receptor 1  / complex
 ENSG00000132475 H3F3B / P84243 / H3 histone family member 3B  / complex
 ENSG00000124151 NCOA3 / Q9Y6Q9 / nuclear receptor coactivator 3  / complex






 

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