ENSG00000173535


Homo sapiens

Features
Gene ID: ENSG00000173535
  
Biological name :TNFRSF10C
  
Synonyms : O14798 / TNF receptor superfamily member 10c / TNFRSF10C
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: p21.3
Gene start: 23102590
Gene end: 23117437
  
Corresponding Affymetrix probe sets: 206222_at (Human Genome U133 Plus 2.0 Array)   210484_s_at (Human Genome U133 Plus 2.0 Array)   211163_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000349324
Ensembl peptide - ENSP00000428235
RefSeq - NM_003841
RefSeq Peptide - NP_003832
swissprot - E5RJI1
swissprot - O14798
Ensembl - ENSG00000173535
  
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hdrENSDARG00000004392Danio rerio
 tnfrsfaENSDARG00000004451Danio rerio
 TNFRSF10BENSGALG00000000452Gallus gallus
 Q9QZM4ENSMUSG00000022074Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UBN6 / TNFRSF10D / TNF receptor superfamily member 10dENSG0000017353052
O00220 / TNFRSF10A / TNF receptor superfamily member 10aENSG0000010468943
O14763 / TNFRSF10B / TNF receptor superfamily member 10bENSG0000012088941


Protein motifs (from Interpro)
Interpro ID Name
 IPR001368  TNFR/NGFR cysteine-rich region
 IPR020465  Tumour necrosis factor receptor 10
 IPR034024  Tumor necrosis factor receptor 10, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042981 regulation of apoptotic process TAS
 biological_processGO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process IBA
 biological_processGO:0097190 apoptotic signaling pathway IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity TAS
 molecular_functionGO:0005031 tumor necrosis factor-activated receptor activity IBA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0045569 TRAIL binding IEA


Pathways (from Reactome)
Pathway description
TP53 Regulates Transcription of Death Receptors and Ligands


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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