ENSGALG00000000452


Gallus gallus

Features
Gene ID: ENSGALG00000000452
  
Biological name :TNFRSF10B
  
Synonyms : TNFRSF10B
  
Possible biological names infered from orthology : O00220 / O14763 / O14798 / Q9QZM4 / Q9UBN6 / TNF receptor superfamily member 10a / TNF receptor superfamily member 10b / TNF receptor superfamily member 10c / TNF receptor superfamily member 10d / TNFRSF10A / TNFRSF10C / TNFRSF10D / Tumor necrosis factor receptor superfamily member 10B
  
Species: Gallus gallus
  
Chr. number: 22
Strand: 1
Band:
Gene start: 1278137
Gene end: 1284564
  
Corresponding Affymetrix probe sets: Gga.4589.1.S1_at (Chicken Array)   Gga.4589.1.S3_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000040157
NCBI entrez gene - 373904     See in Manteia.
RefSeq - XM_015297295
RefSeq - NM_204115
RefSeq - XM_015297293
RefSeq - XM_015297294
RefSeq Peptide - NP_989446
swissprot - Q9IAR7
Ensembl - ENSGALG00000000452
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hdrENSDARG00000004392Danio rerio
 tnfrsfaENSDARG00000004451Danio rerio
 O00220ENSG00000104689Homo sapiens
 O14763ENSG00000120889Homo sapiens
 O14798ENSG00000173535Homo sapiens
 Q9UBN6ENSG00000173530Homo sapiens
 Q9QZM4ENSMUSG00000022074Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DDTNFR23 / death domain-containing tumor necrosis factor receptor superfamily member 23 precursor ENSGALG0000000640714


Protein motifs (from Interpro)
Interpro ID Name
 IPR000488  Death domain
 IPR001368  TNFR/NGFR cysteine-rich region
 IPR011029  Death-like domain superfamily
 IPR020465  Tumour necrosis factor receptor 10


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0032496 response to lipopolysaccharide IBA
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IEA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0097190 apoptotic signaling pathway IBA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005031 tumor necrosis factor-activated receptor activity IBA
 molecular_functionGO:0045569 TRAIL binding IEA


Pathways (from Reactome)
Pathway description
Cell surface interactions at the vascular wall
Regulation by c-FLIP
CASP8 activity is inhibited
Dimerization of procaspase-8
TRAIL signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000008240 CFLAR / CASP8 and FADD-like apoptosis regulator / O15519* / O35732* / CASP8 and FADD-like apoptosis regulator CASP8 and FADD-like apoptosis regulator subunit p43 CASP8 and FADD-like apopto...  / reaction / complex
 ENSGALG00000007625 FADD / Fas associated via death domain / Q13158* / Q61160* / FAS-associated death domain protein *  / reaction / complex
 ENSGALG00000009179 TNFSF10 / TNF superfamily member 10 / P50591* / P50592* / tumor necrosis factor (ligand) superfamily, member 10*  / reaction / complex
 ENSGALG00000000452 TNFRSF10B / O14798* / Q9UBN6* / O00220* / O14763* / Q9QZM4* / TNFRSF10D* / TNFRSF10A* / TNFRSF10C* / TNF receptor superfamily member 10b* / TNF receptor superfamily member 10a* / TNF recept...  / complex / reaction






 

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