ENSG00000175895


Homo sapiens

Features
Gene ID: ENSG00000175895
  
Biological name :PLEKHF2
  
Synonyms : pleckstrin homology and FYVE domain containing 2 / PLEKHF2 / Q9H8W4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q22.1
Gene start: 95133804
Gene end: 95156684
  
Corresponding Affymetrix probe sets: 218640_s_at (Human Genome U133 Plus 2.0 Array)   222699_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000427792
Ensembl peptide - ENSP00000322373
NCBI entrez gene - 79666     See in Manteia.
OMIM - 615208
RefSeq - NM_024613
RefSeq Peptide - NP_078889
swissprot - Q9H8W4
Ensembl - ENSG00000175895
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q7ZUV1ENSDARG00000021141Danio rerio
 PLEKHF2ENSGALG00000040248Gallus gallus
 Q91WB4ENSMUSG00000049969Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q96S99 / PLEKHF1 / pleckstrin homology and FYVE domain containing 1ENSG0000016628955
FGD6 / Q6ZV73 / FYVE, RhoGEF and PH domain containing 6ENSG0000018026333
FGD1 / P98174 / FYVE, RhoGEF and PH domain containing 1ENSG0000010230227
FGD3 / Q5JSP0 / FYVE, RhoGEF and PH domain containing 3ENSG0000012708425
FGD2 / Q7Z6J4 / FYVE, RhoGEF and PH domain containing 2ENSG0000014619225
FGD4 / Q96M96 / FYVE, RhoGEF and PH domain containing 4ENSG0000013913224
FGD5 / Q6ZNL6 / FYVE, RhoGEF and PH domain containing 5ENSG0000015478324


Protein motifs (from Interpro)
Interpro ID Name
 IPR000306  FYVE zinc finger
 IPR001849  Pleckstrin homology domain
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011993  PH-like domain superfamily
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR017455  Zinc finger, FYVE-related


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0015031 protein transport IEA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030133 transport vesicle IDA
 cellular_componentGO:0031901 early endosome membrane IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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