ENSG00000183741


Homo sapiens

Features
Gene ID: ENSG00000183741
  
Biological name :CBX6
  
Synonyms : CBX6 / chromobox 6 / O95503
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: -1
Band: q13.1
Gene start: 38861450
Gene end: 38872314
  
Corresponding Affymetrix probe sets: 202047_s_at (Human Genome U133 Plus 2.0 Array)   202048_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000384490
Ensembl peptide - ENSP00000216083
NCBI entrez gene - 23466     See in Manteia.
OMIM - 617438
RefSeq - NM_001303494
RefSeq - NM_014292
RefSeq Peptide - NP_001290423
RefSeq Peptide - NP_055107
swissprot - O95503
swissprot - B0QXZ6
Ensembl - ENSG00000183741
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cbx6aENSDARG00000071051Danio rerio
 cbx6bENSDARG00000097543Danio rerio
 CBX6ENSGALG00000036867Gallus gallus
 Cbx6ENSMUSG00000089715Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CBX8 / Q9HC52 / chromobox 8ENSG0000014157036
CBX4 / O00257 / chromobox 4ENSG0000014158227
CBX2 / Q14781 / chromobox 2ENSG0000017389425
CBX7 / O95931 / chromobox 7ENSG0000010030722


Protein motifs (from Interpro)
Interpro ID Name
 IPR000953  Chromo/chromo shadow domain
 IPR016197  Chromo-like domain superfamily
 IPR017984  Chromo domain subgroup
 IPR023779  Chromo domain, conserved site
 IPR023780  Chromo domain
 IPR033773  CBX family C-terminal motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 cellular_componentGO:0000792 heterochromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0031519 PcG protein complex IDA
 molecular_functionGO:0003727 single-stranded RNA binding IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Oxidative Stress Induced Senescence
RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Regulation of PTEN gene transcription


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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