ENSG00000185436


Homo sapiens

Features
Gene ID: ENSG00000185436
  
Biological name :IFNLR1
  
Synonyms : IFNLR1 / interferon lambda receptor 1 / Q8IU57
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.11
Gene start: 24154157
Gene end: 24187959
  
Corresponding Affymetrix probe sets: 1555499_a_at (Human Genome U133 Plus 2.0 Array)   244261_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000363540
Ensembl peptide - ENSP00000327824
Ensembl peptide - ENSP00000328994
Ensembl peptide - ENSP00000363542
Ensembl peptide - ENSP00000363539
NCBI entrez gene - 163702     See in Manteia.
OMIM - 607404
RefSeq - XM_017000479
RefSeq - NM_170743
RefSeq - NM_173064
RefSeq - NM_173065
RefSeq - XM_006710394
RefSeq Peptide - NP_775088
RefSeq Peptide - NP_734464
RefSeq Peptide - NP_775087
swissprot - Q5VTX9
swissprot - Q8IU57
Ensembl - ENSG00000185436
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 K9JA28ENSGALG00000004231Gallus gallus
 Ifnlr1ENSMUSG00000062157Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003961  Fibronectin type III
 IPR013783  Immunoglobulin-like fold
 IPR036116  Fibronectin type III superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002385 mucosal immune response ISS
 biological_processGO:0008285 negative regulation of cell proliferation NAS
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0034342 response to type III interferon ISS
 biological_processGO:0050691 regulation of defense response to virus by host IDA
 biological_processGO:0051607 defense response to virus ISS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0032002 interleukin-28 receptor complex IDA
 molecular_functionGO:0004896 cytokine receptor activity NAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Other interleukin signaling
Interleukin-20 family signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000105397 TYK2 / P29597 / tyrosine kinase 2  / complex / reaction
 ENSG00000243646 IL10RB / Q08334 / interleukin 10 receptor subunit beta  / reaction / complex
 ENSG00000197110 IFNL3 / Q8IZI9 / interferon lambda 3  / complex
 ENSG00000183709 IFNL2 / Q8IZJ0 / interferon lambda 2  / complex
 ENSG00000182393 IFNL1 / Q8IU54 / interferon lambda 1  / reaction / complex
 ENSG00000162434 JAK1 / P23458 / Janus kinase 1  / reaction / complex






 

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