ENSG00000185467


Homo sapiens

Features
Gene ID: ENSG00000185467
  
Biological name :KPNA7
  
Synonyms : A9QM74 / karyopherin subunit alpha 7 / KPNA7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q22.1
Gene start: 99173574
Gene end: 99207506
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000330878
NCBI entrez gene - 402569     See in Manteia.
OMIM - 614107
RefSeq - XM_017012216
RefSeq - NM_001145715
RefSeq - XM_017012214
RefSeq - XM_017012215
RefSeq - XM_011516215
RefSeq - XM_017012208
RefSeq - XM_017012209
RefSeq - XM_017012210
RefSeq - XM_017012211
RefSeq - XM_017012212
RefSeq - XM_017012213
RefSeq Peptide - NP_001139187
swissprot - A9QM74
Ensembl - ENSG00000185467
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kpna7ENSDARG00000027169Danio rerio
 KPNA7ENSGALG00000004665Gallus gallus
 Kpna7ENSMUSG00000038770Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KPNA2 / P52292 / karyopherin subunit alpha 2ENSG0000018248154
KPNA3 / O00505 / karyopherin subunit alpha 3ENSG0000010275343
KPNA4 / O00629 / karyopherin subunit alpha 4ENSG0000018643243
KPNA6 / O60684 / karyopherin subunit alpha 6ENSG0000002580042
KPNA1 / P52294 / karyopherin subunit alpha 1ENSG0000011403042
KPNA5 / O15131 / karyopherin subunit alpha 5ENSG0000019691141


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR002652  Importin-alpha, importin-beta-binding domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024931  Importin subunit alpha
 IPR032413  Atypical Arm repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0006607 NLS-bearing protein import into nucleus IBA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0019054 modulation by virus of host process TAS
 biological_processGO:0075733 intracellular transport of virus TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IBA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0043657 host cell IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0008565 protein transporter activity IBA
 molecular_functionGO:0061608 nuclear import signal receptor activity IEA


Pathways (from Reactome)
Pathway description
ISG15 antiviral mechanism
NS1 Mediated Effects on Host Pathways


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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