ENSG00000025800


Homo sapiens

Features
Gene ID: ENSG00000025800
  
Biological name :KPNA6
  
Synonyms : karyopherin subunit alpha 6 / KPNA6 / O60684
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p35.2
Gene start: 32108038
Gene end: 32176568
  
Corresponding Affymetrix probe sets: 212101_at (Human Genome U133 Plus 2.0 Array)   212102_s_at (Human Genome U133 Plus 2.0 Array)   212103_at (Human Genome U133 Plus 2.0 Array)   226976_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000362728
Ensembl peptide - ENSP00000415677
Ensembl peptide - ENSP00000474234
NCBI entrez gene - 23633     See in Manteia.
OMIM - 610563
RefSeq - XM_005270711
RefSeq - NM_012316
RefSeq Peptide - NP_036448
swissprot - O60684
swissprot - Q5TFJ7
swissprot - S4R3E5
Ensembl - ENSG00000025800
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kpna6ENSDARG00000044980Danio rerio
 KPNA6ENSGALG00000003383Gallus gallus
 Kpna6ENSMUSG00000003731Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KPNA5 / O15131 / karyopherin subunit alpha 5ENSG0000019691185
KPNA1 / P52294 / karyopherin subunit alpha 1ENSG0000011403082
KPNA4 / O00629 / karyopherin subunit alpha 4ENSG0000018643248
KPNA3 / O00505 / karyopherin subunit alpha 3ENSG0000010275347
KPNA2 / P52292 / karyopherin subunit alpha 2ENSG0000018248146
KPNA7 / A9QM74 / karyopherin subunit alpha 7ENSG0000018546740


Protein motifs (from Interpro)
Interpro ID Name
 IPR000225  Armadillo
 IPR002652  Importin-alpha, importin-beta-binding domain
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold
 IPR024931  Importin subunit alpha
 IPR032413  Atypical Arm repeat


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006606 protein import into nucleus IEA
 biological_processGO:0006607 NLS-bearing protein import into nucleus TAS
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0060135 maternal process involved in female pregnancy IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005643 nuclear pore IBA
 cellular_componentGO:0005654 nucleoplasm IBA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IBA
 cellular_componentGO:0016020 membrane HDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008139 nuclear localization sequence binding IBA
 molecular_functionGO:0008565 protein transporter activity IEA
 molecular_functionGO:0061608 nuclear import signal receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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