ENSG00000185924


Homo sapiens

Features
Gene ID: ENSG00000185924
  
Biological name :RTN4RL1
  
Synonyms : Q86UN2 / reticulon 4 receptor like 1 / RTN4RL1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p13.3
Gene start: 1934677
Gene end: 2025345
  
Corresponding Affymetrix probe sets: 230700_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000330631
NCBI entrez gene - 146760     See in Manteia.
OMIM - 610461
RefSeq - NM_178568
RefSeq Peptide - NP_848663
swissprot - Q86UN2
Ensembl - ENSG00000185924
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rtn4rl1aENSDARG00000007856Danio rerio
 rtn4rl1bENSDARG00000098528Danio rerio
 RTN4RL1ENSGALG00000021589Gallus gallus
 Q8K0S5ENSMUSG00000045287Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q86UN3 / RTN4RL2 / reticulon 4 receptor like 2ENSG0000018690744
RTN4R / Q9BZR6 / reticulon 4 receptorENSG0000004060841
LRRC24 / Q50LG9 / leucine rich repeat containing 24ENSG0000025440223
LRRC26 / Q2I0M4 / leucine rich repeat containing 26ENSG0000018470920
LRRC52 / Q8N7C0 / leucine rich repeat containing 52ENSG0000016276318
LRRC55 / Q6ZSA7 / leucine rich repeat containing 55ENSG0000018390817
LRRC38 / Q5VT99 / leucine rich repeat containing 38ENSG0000016249417
LRTM2 / Q8N967 / leucine rich repeats and transmembrane domains 2ENSG0000016615915
LRTM1 / Q9HBL6 / leucine rich repeats and transmembrane domains 1ENSG0000014477115


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0010977 negative regulation of neuron projection development IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0022038 corpus callosum development IEA
 biological_processGO:0031103 axon regeneration TAS
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0048681 negative regulation of axon regeneration IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043204 perikaryon IEA
 cellular_componentGO:0045121 membrane raft IEA
 cellular_componentGO:0046658 anchored component of plasma membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0035374 chondroitin sulfate binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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