ENSG00000162494


Homo sapiens

Features
Gene ID: ENSG00000162494
  
Biological name :LRRC38
  
Synonyms : leucine rich repeat containing 38 / LRRC38 / Q5VT99
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p36.21
Gene start: 13474977
Gene end: 13514048
  
Corresponding Affymetrix probe sets: 1558375_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000365253
NCBI entrez gene - 126755     See in Manteia.
OMIM - 615212
RefSeq - NM_001010847
RefSeq Peptide - NP_001010847
swissprot - Q5VT99
Ensembl - ENSG00000162494
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrrc38aENSDARG00000075147Danio rerio
 lrrc38bENSDARG00000087745Danio rerio
 LRRC38ENSGALG00000004097Gallus gallus
 A2VDH3ENSMUSG00000028584Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRRC55 / Q6ZSA7 / leucine rich repeat containing 55ENSG0000018390834
LRRC24 / Q50LG9 / leucine rich repeat containing 24ENSG0000025440232
LRRC26 / Q2I0M4 / leucine rich repeat containing 26ENSG0000018470931
LRRC52 / Q8N7C0 / leucine rich repeat containing 52ENSG0000016276329
Q86UN3 / RTN4RL2 / reticulon 4 receptor like 2ENSG0000018690729
RTN4R / Q9BZR6 / reticulon 4 receptorENSG0000004060827
Q86UN2 / RTN4RL1 / reticulon 4 receptor like 1ENSG0000018592426
LRTM2 / Q8N967 / leucine rich repeats and transmembrane domains 2ENSG0000016615925
LRTM1 / Q9HBL6 / leucine rich repeats and transmembrane domains 1ENSG0000014477125


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007409 axonogenesis IBA
 biological_processGO:0071805 potassium ion transmembrane transport IDA
 biological_processGO:1903818 positive regulation of voltage-gated potassium channel activity IDA
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane ISS
 cellular_componentGO:0008076 voltage-gated potassium channel complex IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0044325 ion channel binding IPI
 molecular_functionGO:0099104 potassium channel activator activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr