ENSG00000144771


Homo sapiens

Features
Gene ID: ENSG00000144771
  
Biological name :LRTM1
  
Synonyms : leucine rich repeats and transmembrane domains 1 / LRTM1 / Q9HBL6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p14.3
Gene start: 54918237
Gene end: 54967088
  
Corresponding Affymetrix probe sets: 221612_at (Human Genome U133 Plus 2.0 Array)   91580_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000273286
Ensembl peptide - ENSP00000419772
NCBI entrez gene - 57408     See in Manteia.
RefSeq - NM_020678
RefSeq - NM_001304389
RefSeq Peptide - NP_001291318
RefSeq Peptide - NP_065729
swissprot - Q9HBL6
Ensembl - ENSG00000144771
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrtm1ENSDARG00000098742Danio rerio
 LRTM1ENSGALG00000005404Gallus gallus
 Lrtm1ENSMUSG00000045776Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRTM2 / Q8N967 / leucine rich repeats and transmembrane domains 2ENSG0000016615937
LRRC24 / Q50LG9 / leucine rich repeat containing 24ENSG0000025440226
Q86UN3 / RTN4RL2 / reticulon 4 receptor like 2ENSG0000018690724
RTN4R / Q9BZR6 / reticulon 4 receptorENSG0000004060823
LRRC38 / Q5VT99 / leucine rich repeat containing 38ENSG0000016249421
LRRC26 / Q2I0M4 / leucine rich repeat containing 26ENSG0000018470920
LRRC52 / Q8N7C0 / leucine rich repeat containing 52ENSG0000016276319
LRRC55 / Q6ZSA7 / leucine rich repeat containing 55ENSG0000018390819
Q86UN2 / RTN4RL1 / reticulon 4 receptor like 1ENSG0000018592419


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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