ENSG00000186907


Homo sapiens

Features
Gene ID: ENSG00000186907
  
Biological name :RTN4RL2
  
Synonyms : Q86UN3 / reticulon 4 receptor like 2 / RTN4RL2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q12.1
Gene start: 57460549
Gene end: 57477534
  
Corresponding Affymetrix probe sets: 229345_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378552
Ensembl peptide - ENSP00000435606
Ensembl peptide - ENSP00000335397
NCBI entrez gene - 349667     See in Manteia.
OMIM - 610462
RefSeq - NM_178570
RefSeq Peptide - NP_848665
swissprot - G3V1D7
swissprot - Q86UN3
Ensembl - ENSG00000186907
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rtn4rl2aENSDARG00000052012Danio rerio
 rtn4rl2bENSDARG00000037495Danio rerio
 RTN4RL2ENSGALG00000032903Gallus gallus
 Q7M6Z0ENSMUSG00000050896Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q86UN2 / RTN4RL1 / reticulon 4 receptor like 1ENSG0000018592446
RTN4R / Q9BZR6 / reticulon 4 receptorENSG0000004060841
LRRC24 / Q50LG9 / leucine rich repeat containing 24ENSG0000025440227
LRRC26 / Q2I0M4 / leucine rich repeat containing 26ENSG0000018470921
LRRC55 / Q6ZSA7 / leucine rich repeat containing 55ENSG0000018390821
LRRC38 / Q5VT99 / leucine rich repeat containing 38ENSG0000016249420
LRTM1 / Q9HBL6 / leucine rich repeats and transmembrane domains 1ENSG0000014477120
LRTM2 / Q8N967 / leucine rich repeats and transmembrane domains 2ENSG0000016615919
LRRC52 / Q8N7C0 / leucine rich repeat containing 52ENSG0000016276317


Protein motifs (from Interpro)
Interpro ID Name
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0006501 C-terminal protein lipidation TAS
 biological_processGO:0007166 cell surface receptor signaling pathway ISS
 biological_processGO:0010977 negative regulation of neuron projection development ISS
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0022038 corpus callosum development IEA
 biological_processGO:0031103 axon regeneration TAS
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030424 axon ISS
 cellular_componentGO:0030425 dendrite IEA
 cellular_componentGO:0031225 anchored component of membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043005 neuron projection ISS
 cellular_componentGO:0043204 perikaryon ISS
 cellular_componentGO:0045121 membrane raft ISS
 cellular_componentGO:0046658 anchored component of plasma membrane IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Post-translational modification: synthesis of GPI-anchored proteins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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