ENSG00000166159


Homo sapiens

Features
Gene ID: ENSG00000166159
  
Biological name :LRTM2
  
Synonyms : leucine rich repeats and transmembrane domains 2 / LRTM2 / Q8N967
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: p13.33
Gene start: 1820267
Gene end: 1836752
  
Corresponding Affymetrix probe sets: 1558530_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000299194
Ensembl peptide - ENSP00000438678
Ensembl peptide - ENSP00000444104
Ensembl peptide - ENSP00000444737
Ensembl peptide - ENSP00000446278
NCBI entrez gene - 654429     See in Manteia.
RefSeq - XM_017019848
RefSeq - NM_001039029
RefSeq - NM_001163925
RefSeq - NM_001163926
RefSeq - XM_011521015
RefSeq Peptide - NP_001034118
RefSeq Peptide - NP_001157397
RefSeq Peptide - NP_001157398
swissprot - F5H2B4
swissprot - Q8N967
swissprot - F5GZY9
Ensembl - ENSG00000166159
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lrtm2aENSDARG00000045483Danio rerio
 lrtm2bENSDARG00000045811Danio rerio
 LRTM2ENSGALG00000026214Gallus gallus
 Lrtm2ENSMUSG00000055003Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LRTM1 / Q9HBL6 / leucine rich repeats and transmembrane domains 1ENSG0000014477134
LRRC55 / Q6ZSA7 / leucine rich repeat containing 55ENSG0000018390824
LRRC24 / Q50LG9 / leucine rich repeat containing 24ENSG0000025440224
Q86UN3 / RTN4RL2 / reticulon 4 receptor like 2ENSG0000018690722
LRRC26 / Q2I0M4 / leucine rich repeat containing 26ENSG0000018470921
RTN4R / Q9BZR6 / reticulon 4 receptorENSG0000004060821
LRRC38 / Q5VT99 / leucine rich repeat containing 38ENSG0000016249420
LRRC52 / Q8N7C0 / leucine rich repeat containing 52ENSG0000016276319
Q86UN2 / RTN4RL1 / reticulon 4 receptor like 1ENSG0000018592418


Protein motifs (from Interpro)
Interpro ID Name
 IPR000372  Leucine-rich repeat N-terminal domain
 IPR000483  Cysteine-rich flanking region, C-terminal
 IPR001611  Leucine-rich repeat
 IPR003591  Leucine-rich repeat, typical subtype
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006469 negative regulation of protein kinase activity IBA
 biological_processGO:0019221 cytokine-mediated signaling pathway IBA
 biological_processGO:0046426 negative regulation of JAK-STAT cascade IBA
 biological_processGO:0051965 positive regulation of synapse assembly IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004860 protein kinase inhibitor activity IBA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr