ENSG00000185988


Homo sapiens

Features
Gene ID: ENSG00000185988
  
Biological name :PLK5
  
Synonyms : PLK5 / polo like kinase 5 / Q496M5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: p13.3
Gene start: 1524074
Gene end: 1536046
  
Corresponding Affymetrix probe sets: 1558897_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000468376
Ensembl peptide - ENSP00000493341
Ensembl peptide - ENSP00000465896
Ensembl peptide - ENSP00000466248
NCBI entrez gene - 126520     See in Manteia.
RefSeq - NM_001243079
RefSeq Peptide - NP_001230008
swissprot - A0A286YFL1
swissprot - Q496M5
Ensembl - ENSG00000185988
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Plk5ENSMUSG00000035486Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLK3 / Q9H4B4 / polo like kinase 3ENSG0000017384637
PLK2 / Q9NYY3 / polo like kinase 2ENSG0000014563232
PLK1 / P53350 / polo like kinase 1ENSG0000016685126
PLK4 / O00444 / polo like kinase 4ENSG0000014273122


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR011009  Protein kinase-like domain superfamily
 IPR033701  First polo-box domain
 IPR036947  POLO box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002357 defense response to tumor cell IDA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010976 positive regulation of neuron projection development IDA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0042981 regulation of apoptotic process IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0071363 cellular response to growth factor stimulus IDA
 biological_processGO:2000045 regulation of G1/S transition of mitotic cell cycle IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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