ENSMUSG00000035486


Mus musculus

Features
Gene ID: ENSMUSG00000035486
  
Biological name :Plk5
  
Synonyms : Mus musculus polo like kinase 5 (Plk5), transcript variant 2, mRNA. / Plk5 / Q4FZD7
  
Possible biological names infered from orthology : polo like kinase 5 / Q496M5
  
Species: Mus musculus
  
Chr. number: 10
Strand: 1
Band: C1
Gene start: 80356459
Gene end: 80365489
  
Corresponding Affymetrix probe sets: 10364792 (MoGene1.0st)   1434984_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000044400
Ensembl peptide - ENSMUSP00000100988
NCBI entrez gene - 216166     See in Manteia.
MGI - MGI:3026984
RefSeq - XM_006513502
RefSeq - NM_001347124
RefSeq - NM_183152
RefSeq - XM_006513498
RefSeq - XM_006513499
RefSeq - XM_006513500
RefSeq - XM_006513501
RefSeq Peptide - NP_001334053
RefSeq Peptide - NP_898975
swissprot - Q4FZD7
swissprot - G3X967
Ensembl - ENSMUSG00000035486
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PLK5ENSG00000185988Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Plk3 / serine/threonine-protein kinase PLK3 isoform 2 / Q9H4B4* / polo like kinase 3*ENSMUSG0000002868041
Plk2 / P53351 / Serine/threonine-protein kinase PLK2 / Q9NYY3* / polo like kinase 2*ENSMUSG0000002170138
Plk1 / Q07832 / polo like kinase 1 / P53350*ENSMUSG0000003086734
Plk4 / Q64702 / Serine/threonine-protein kinase PLK4 / O00444* / polo like kinase 4*ENSMUSG0000002575824


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR000959  POLO box domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR033701  First polo-box domain
 IPR036947  POLO box domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002357 defense response to tumor cell ISO
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0010976 positive regulation of neuron projection development ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0042981 regulation of apoptotic process IMP
 biological_processGO:0051301 cell division IEA
 biological_processGO:0071363 cellular response to growth factor stimulus ISO
 biological_processGO:2000045 regulation of G1/S transition of mitotic cell cycle ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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