ENSG00000188766


Homo sapiens

Features
Gene ID: ENSG00000188766
  
Biological name :SPRED3
  
Synonyms : Q2MJR0 / SPRED3 / sprouty related EVH1 domain containing 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.2
Gene start: 38388421
Gene end: 38399587
  
Corresponding Affymetrix probe sets: 230046_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000465713
Ensembl peptide - ENSP00000467532
Ensembl peptide - ENSP00000467540
Ensembl peptide - ENSP00000345405
Ensembl peptide - ENSP00000466568
NCBI entrez gene - 399473     See in Manteia.
OMIM - 609293
RefSeq - XM_011526978
RefSeq - NM_001042522
RefSeq - XM_006723219
RefSeq Peptide - NP_001035987
swissprot - K7EKP4
swissprot - Q2MJR0
swissprot - K7EPT9
swissprot - K7EPU5
Ensembl - ENSG00000188766
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 spred3ENSDARG00000040358Danio rerio
 Spred3ENSMUSG00000037239Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q7Z698 / SPRED2 / sprouty related EVH1 domain containing 2ENSG0000019836938
Q7Z699 / SPRED1 / sprouty related EVH1 domain containing 1ENSG0000016606836
EVL / Q9UI08 / Enah/Vasp-likeENSG0000019640518
VASP / P50552 / vasodilator stimulated phosphoproteinENSG0000012575318
ENAH / Q8N8S7 / ENAH, actin regulatorENSG0000015438017


Protein motifs (from Interpro)
Interpro ID Name
 IPR000697  WH1/EVH1 domain
 IPR007875  Sprouty
 IPR011993  PH-like domain superfamily
 IPR023337  c-Kit-binding domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009966 regulation of signal transduction IEA
 cellular_componentGO:0016020 membrane IEA


Pathways (from Reactome)
Pathway description
Regulation of RAS by GAPs
Signaling by RAS mutants


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000188766 Q2MJR0 / SPRED3 / sprouty related EVH1 domain containing 3  / complex






 

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contact: otassy@igbmc.fr