ENSG00000154380


Homo sapiens

Features
Gene ID: ENSG00000154380
  
Biological name :ENAH
  
Synonyms : ENAH / ENAH, actin regulator / Q8N8S7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q42.12
Gene start: 225486835
Gene end: 225653142
  
Corresponding Affymetrix probe sets: 1553672_at (Human Genome U133 Plus 2.0 Array)   217820_s_at (Human Genome U133 Plus 2.0 Array)   222433_at (Human Genome U133 Plus 2.0 Array)   222434_at (Human Genome U133 Plus 2.0 Array)   228310_at (Human Genome U133 Plus 2.0 Array)   228553_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000489607
Ensembl peptide - ENSP00000284563
Ensembl peptide - ENSP00000355808
Ensembl peptide - ENSP00000355809
Ensembl peptide - ENSP00000489106
NCBI entrez gene - 55740     See in Manteia.
OMIM - 609061
RefSeq - XM_017001757
RefSeq - XM_017001751
RefSeq - XM_017001752
RefSeq - XM_017001753
RefSeq - XM_017001754
RefSeq - XM_017001755
RefSeq - XM_017001756
RefSeq - NM_001008493
RefSeq - NM_018212
RefSeq - XM_005273187
RefSeq - XM_011544229
RefSeq - XM_017001746
RefSeq - XM_017001747
RefSeq - XM_017001748
RefSeq - XM_017001749
RefSeq - XM_017001750
RefSeq Peptide - NP_001008493
RefSeq Peptide - NP_060682
swissprot - A0A0U1RRM6
swissprot - A0A0U1RQP7
swissprot - Q8N8S7
swissprot - A0A075B6E5
Ensembl - ENSG00000154380
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 enahENSDARG00000032049Danio rerio
 ENAHENSGALG00000009303Gallus gallus
 EnahENSMUSG00000022995Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
EVL / Q9UI08 / Enah/Vasp-likeENSG0000019640538
VASP / P50552 / vasodilator stimulated phosphoproteinENSG0000012575332
Q7Z699 / SPRED1 / sprouty related EVH1 domain containing 1ENSG0000016606813
Q7Z698 / SPRED2 / sprouty related EVH1 domain containing 2ENSG0000019836913
Q2MJR0 / SPRED3 / sprouty related EVH1 domain containing 3ENSG0000018876612


Protein motifs (from Interpro)
Interpro ID Name
 IPR000697  WH1/EVH1 domain
 IPR011993  PH-like domain superfamily
 IPR014885  VASP tetramerisation
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007411 axon guidance TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005925 focal adhesion IEA
 cellular_componentGO:0030027 lamellipodium IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0045202 synapse IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0050699 WW domain binding IPI


Pathways (from Reactome)
Pathway description
Generation of second messenger molecules
Signaling by ROBO receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000082074 FYB1 / O15117 / FYN binding protein 1  / reaction / complex
 ENSG00000043462 LCP2 / Q13094 / lymphocyte cytosolic protein 2  / reaction / complex
 ENSG00000145147 SLIT2 / O94813 / slit guidance ligand 2  / reaction / complex
 ENSG00000169855 ROBO1 / Q9Y6N7 / roundabout guidance receptor 1  / reaction / complex






 

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