ENSG00000196074


Homo sapiens

Features
Gene ID: ENSG00000196074
  
Biological name :SYCP2
  
Synonyms : Q9BX26 / SYCP2 / synaptonemal complex protein 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.33
Gene start: 59863563
Gene end: 59933655
  
Corresponding Affymetrix probe sets: 206546_at (Human Genome U133 Plus 2.0 Array)   237920_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000404358
Ensembl peptide - ENSP00000350162
Ensembl peptide - ENSP00000360040
Ensembl peptide - ENSP00000399300
Ensembl peptide - ENSP00000402456
NCBI entrez gene - 10388     See in Manteia.
OMIM - 604105
RefSeq - XM_017027592
RefSeq - XM_017027587
RefSeq - XM_017027588
RefSeq - XM_017027589
RefSeq - XM_017027590
RefSeq - XM_017027591
RefSeq - NM_014258
RefSeq - XM_011528487
RefSeq - XM_011528488
RefSeq - XM_011528489
RefSeq - XM_011528490
RefSeq - XM_011528493
RefSeq - XM_017027586
RefSeq Peptide - NP_055073
swissprot - A2A341
swissprot - A2A340
swissprot - A2A2M9
swissprot - Q9BX26
Ensembl - ENSG00000196074
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sycp2ENSDARG00000088950Danio rerio
 SYCP2ENSGALG00000045232Gallus gallus
 Sycp2ENSMUSG00000060445Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q5T4T6 / SYCP2L / synaptonemal complex protein 2 likeENSG0000015315714


Protein motifs (from Interpro)
Interpro ID Name
 IPR024832  Synaptonemal complex protein 2
 IPR024835  Synaptonemal complex protein 1/2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007130 synaptonemal complex assembly NAS
 biological_processGO:0007140 male meiotic nuclear division IEA
 biological_processGO:0007143 female meiotic nuclear division IEA
 biological_processGO:0009566 fertilization IEA
 biological_processGO:0009887 animal organ morphogenesis IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0048808 male genitalia morphogenesis IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0000795 synaptonemal complex NAS
 cellular_componentGO:0000800 lateral element ISS
 cellular_componentGO:0005634 nucleus NAS
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003677 DNA binding NAS
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Meiotic synapsis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000188486 H2AFX / P16104 / H2A histone family member X  / complex
 ENSG00000139351 SYCP3 / Q8IZU3 / synaptonemal complex protein 3  / complex
 ENSG00000276180 P62805 / HIST1H4I / histone cluster 1 H4 family member i  / complex
 ENSG00000012048 BRCA1 / P38398 / BRCA1, DNA repair associated  / reaction / complex
 ENSG00000168148 Q16695 / HIST3H3 / histone cluster 3 H3  / complex
 ENSG00000175054 ATR / Q13535 / ATR serine/threonine kinase  / reaction / complex






 

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