ENSG00000196975


Homo sapiens

Features
Gene ID: ENSG00000196975
  
Biological name :ANXA4
  
Synonyms : annexin A4 / ANXA4 / P09525
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p13.3
Gene start: 69644425
Gene end: 69827100
  
Corresponding Affymetrix probe sets: 201301_s_at (Human Genome U133 Plus 2.0 Array)   201302_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000489490
Ensembl peptide - ENSP00000377833
Ensembl peptide - ENSP00000386756
Ensembl peptide - ENSP00000489316
Ensembl peptide - ENSP00000489464
NCBI entrez gene - 307     See in Manteia.
OMIM - 106491
RefSeq - XM_017003944
RefSeq - NM_001153
RefSeq - NM_001320698
RefSeq - NM_001320700
RefSeq - NM_001320702
RefSeq - XM_017003943
RefSeq Peptide - NP_001307627
RefSeq Peptide - NP_001307629
RefSeq Peptide - NP_001307631
RefSeq Peptide - NP_001144
swissprot - Q6LES2
swissprot - A0A0U1RRE7
swissprot - Q6P452
swissprot - B4E1S2
swissprot - A0A1Y8EKW3
swissprot - P09525
Ensembl - ENSG00000196975
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 anxa4ENSDARG00000036456Danio rerio
 ANXA4ENSGALG00000038783Gallus gallus
 Anxa4ENSMUSG00000029994Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANXA5 / P08758 / annexin A5ENSG0000016411158
ANXA11 / P50995 / annexin A11ENSG0000012235957
Q5VT79 / ANXA8L1 / annexin A8 like 1ENSG0000026423055
ANXA8 / P13928 / annexin A8ENSG0000026519055
ANXA6 / P08133 / annexin A6ENSG0000019704354
ANXA3 / P12429 / annexin A3ENSG0000013877252
ANXA2 / P07355 / annexin A2ENSG0000018271848
ANXA7 / P20073 / annexin A7ENSG0000013827948
ANXA13 / P27216 / annexin A13ENSG0000010453746
ANXA1 / P04083 / annexin A1ENSG0000013504645


Protein motifs (from Interpro)
Interpro ID Name
 IPR001464  Annexin
 IPR002391  Annexin A4
 IPR002392  Annexin A5
 IPR018252  Annexin repeat, conserved site
 IPR018502  Annexin repeat
 IPR037104  Annexin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IDA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0030855 epithelial cell differentiation IEP
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0050819 negative regulation of coagulation IEA
 biological_processGO:2000483 negative regulation of interleukin-8 secretion IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0012506 vesicle membrane IDA
 cellular_componentGO:0031965 nuclear membrane IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0004859 phospholipase inhibitor activity NAS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0048306 calcium-dependent protein binding IPI
 molecular_functionGO:0051059 NF-kappaB binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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