ENSG00000164111


Homo sapiens

Features
Gene ID: ENSG00000164111
  
Biological name :ANXA5
  
Synonyms : annexin A5 / ANXA5 / P08758
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q27
Gene start: 121667955
Gene end: 121697113
  
Corresponding Affymetrix probe sets: 200782_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000296511
Ensembl peptide - ENSP00000427135
Ensembl peptide - ENSP00000424199
Ensembl peptide - ENSP00000424106
Ensembl peptide - ENSP00000421421
NCBI entrez gene - 308     See in Manteia.
OMIM - 131230
RefSeq - NM_001154
RefSeq Peptide - NP_001145
swissprot - D6RBL5
swissprot - D6RBE9
swissprot - P08758
swissprot - E9PHT9
swissprot - V9HWE0
swissprot - D6RCN3
Ensembl - ENSG00000164111
  
Related genetic diseases (OMIM): 614391 - {Pregnancy loss, recurrent, susceptibility to, 3}, 614391
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 anxa5aENSDARG00000026406Danio rerio
 anxa5bENSDARG00000016470Danio rerio
 ANXA5ENSGALG00000011885Gallus gallus
 Anxa5ENSMUSG00000027712Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANXA4 / P09525 / annexin A4ENSG0000019697558
ANXA6 / P08133 / annexin A6ENSG0000019704358
Q5VT79 / ANXA8L1 / annexin A8 like 1ENSG0000026423056
ANXA8 / P13928 / annexin A8ENSG0000026519055
ANXA11 / P50995 / annexin A11ENSG0000012235953
ANXA3 / P12429 / annexin A3ENSG0000013877249
ANXA7 / P20073 / annexin A7ENSG0000013827948
ANXA2 / P07355 / annexin A2ENSG0000018271845
ANXA1 / P04083 / annexin A1ENSG0000013504643
ANXA13 / P27216 / annexin A13ENSG0000010453743


Protein motifs (from Interpro)
Interpro ID Name
 IPR001464  Annexin
 IPR002392  Annexin A5
 IPR018252  Annexin repeat, conserved site
 IPR018502  Annexin repeat
 IPR037104  Annexin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007596 blood coagulation IEA
 biological_processGO:0007599 hemostasis IEA
 biological_processGO:0010033 response to organic substance IEA
 biological_processGO:0043066 negative regulation of apoptotic process TAS
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0050819 negative regulation of coagulation IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0009897 external side of plasma membrane IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0072563 endothelial microparticle IEA
 molecular_functionGO:0004859 phospholipase inhibitor activity TAS
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding TAS
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IEA


Pathways (from Reactome)
Pathway description
Platelet degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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