ENSG00000197043


Homo sapiens

Features
Gene ID: ENSG00000197043
  
Biological name :ANXA6
  
Synonyms : annexin A6 / ANXA6 / P08133
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q33.1
Gene start: 151100712
Gene end: 151157882
  
Corresponding Affymetrix probe sets: 200982_s_at (Human Genome U133 Plus 2.0 Array)   244250_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000346550
Ensembl peptide - ENSP00000366980
Ensembl peptide - ENSP00000431086
Ensembl peptide - ENSP00000431078
Ensembl peptide - ENSP00000430826
Ensembl peptide - ENSP00000430663
Ensembl peptide - ENSP00000430572
Ensembl peptide - ENSP00000430517
Ensembl peptide - ENSP00000430429
Ensembl peptide - ENSP00000430420
Ensembl peptide - ENSP00000428916
NCBI entrez gene - 309     See in Manteia.
OMIM - 114070
RefSeq - NM_001193544
RefSeq - NM_001155
RefSeq - XM_005268432
RefSeq Peptide - NP_001146
RefSeq Peptide - NP_001180473
swissprot - E5RIU8
swissprot - E5RI05
swissprot - E5RFF0
swissprot - E7EMC6
swissprot - H0YC77
swissprot - P08133
swissprot - A0A0S2Z2Z6
swissprot - E5RK69
swissprot - E5RK63
swissprot - E5RJR0
swissprot - E5RJF5
Ensembl - ENSG00000197043
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 anxa6ENSDARG00000013335Danio rerio
 ANXA6ENSGALG00000004357Gallus gallus
 Anxa6ENSMUSG00000018340Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ANXA5 / P08758 / annexin A5ENSG0000016411127
ANXA11 / P50995 / annexin A11ENSG0000012235927
ANXA4 / P09525 / annexin A4ENSG0000019697526
ANXA8 / P13928 / annexin A8ENSG0000026519025
Q5VT79 / ANXA8L1 / annexin A8 like 1ENSG0000026423025
ANXA3 / P12429 / annexin A3ENSG0000013877224
ANXA2 / P07355 / annexin A2ENSG0000018271823
ANXA1 / P04083 / annexin A1ENSG0000013504621
ANXA7 / P20073 / annexin A7ENSG0000013827921
ANXA13 / P27216 / annexin A13ENSG0000010453721


Protein motifs (from Interpro)
Interpro ID Name
 IPR001464  Annexin
 IPR002391  Annexin A4
 IPR002393  Annexin A6
 IPR018252  Annexin repeat, conserved site
 IPR018502  Annexin repeat
 IPR037104  Annexin superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006816 calcium ion transport IEA
 biological_processGO:0006937 regulation of muscle contraction IEA
 biological_processGO:0034220 ion transmembrane transport IMP
 biological_processGO:0051260 protein homooligomerization IMP
 biological_processGO:0051560 mitochondrial calcium ion homeostasis IEA
 biological_processGO:0097190 apoptotic signaling pathway IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005765 lysosomal membrane IDA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0031902 late endosome membrane IDA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005525 GTP binding IMP
 molecular_functionGO:0005544 calcium-dependent phospholipid binding IEA
 molecular_functionGO:0008289 lipid binding IMP
 molecular_functionGO:0015276 ligand-gated ion channel activity IMP
 molecular_functionGO:0015485 cholesterol binding IDA
 molecular_functionGO:0042803 protein homodimerization activity IMP
 molecular_functionGO:0048306 calcium-dependent protein binding IPI


Pathways (from Reactome)
Pathway description
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000177238 Q6ZMU5 / TRIM72 / tripartite motif containing 72  / reaction
 ENSG00000182718 ANXA2 / P07355 / annexin A2  / reaction
 ENSG00000135046 ANXA1 / P04083 / annexin A1  / reaction
 ENSG00000135636 DYSF / O75923 / dysferlin  / reaction
 ENSG00000182533 CAV3 / P56539 / caveolin 3  / reaction






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr