ENSG00000177238


Homo sapiens

Features
Gene ID: ENSG00000177238
  
Biological name :TRIM72
  
Synonyms : Q6ZMU5 / TRIM72 / tripartite motif containing 72
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 31214021
Gene end: 31231537
  
Corresponding Affymetrix probe sets: 1554803_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000312675
Ensembl peptide - ENSP00000481813
NCBI entrez gene - 493829     See in Manteia.
OMIM - 613288
RefSeq - XM_017023254
RefSeq - NM_001008274
RefSeq Peptide - NP_001008275
swissprot - Q6ZMU5
Ensembl - ENSG00000177238
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q1XH17ENSMUSG00000042828Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q86XT4 / TRIM50 / tripartite motif containing 50ENSG0000014675533
TRIM7 / Q9C029 / tripartite motif containing 7ENSG0000014605427
P14373 / TRIM27 / tripartite motif containing 27ENSG0000020471326
Q8WV44 / TRIM41 / tripartite motif containing 41ENSG0000014606325
Q9UPQ4 / TRIM35 / tripartite motif containing 35ENSG0000010422824
Q86WT6 / TRIM69 / tripartite motif containing 69ENSG0000018588024
Q9UDY6 / TRIM10 / tripartite motif containing 10ENSG0000020461323
Q9BVG3 / TRIM62 / tripartite motif containing 62ENSG0000011652523
Q12899 / TRIM26 / tripartite motif containing 26ENSG0000023412723
MEFV / O15553 / MEFV, pyrin innate immunity regulatorENSG0000010331321
Q9C019 / TRIM15 / tripartite motif containing 15ENSG0000020461019
Q9BZY9 / TRIM31 / tripartite motif containing 31ENSG0000020461616
Q86UV6 / TRIM74 / tripartite motif containing 74ENSG0000015542814
Q86UV7 / TRIM73 / tripartite motif containing 73ENSG0000017880914
Q96A61 / TRIM52 / tripartite motif containing 52ENSG0000018371810


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR001870  B30.2/SPRY domain
 IPR003877  SPRY domain
 IPR003879  Butyrophylin-like, SPRY domain
 IPR006574  SPRY-associated
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017907  Zinc finger, RING-type, conserved site
 IPR035038  Tripartite motif-containing protein 72


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001778 plasma membrane repair ISS
 biological_processGO:0003012 muscle system process ISS
 biological_processGO:0006887 exocytosis IEA
 biological_processGO:0006936 muscle contraction TAS
 biological_processGO:0007517 muscle organ development ISS
 biological_processGO:0010832 negative regulation of myotube differentiation IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway IEA
 biological_processGO:0046627 negative regulation of insulin receptor signaling pathway IEA
 biological_processGO:0051260 protein homooligomerization ISS
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane TAS
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0042383 sarcolemma ISS
 molecular_functionGO:0001786 phosphatidylserine binding ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0031624 ubiquitin conjugating enzyme binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IEA


Pathways (from Reactome)
Pathway description
Smooth Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000182533 CAV3 / P56539 / caveolin 3  / reaction / complex
 ENSG00000135636 DYSF / O75923 / dysferlin  / reaction / complex
 ENSG00000182718 ANXA2 / P07355 / annexin A2  / reaction
 ENSG00000135046 ANXA1 / P04083 / annexin A1  / reaction
 ENSG00000197043 ANXA6 / P08133 / annexin A6  / reaction






 

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