ENSG00000146755


Homo sapiens

Features
Gene ID: ENSG00000146755
  
Biological name :TRIM50
  
Synonyms : Q86XT4 / TRIM50 / tripartite motif containing 50
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q11.23
Gene start: 73312539
Gene end: 73328082
  
Corresponding Affymetrix probe sets: 1556554_at (Human Genome U133 Plus 2.0 Array)   231014_at (Human Genome U133 Plus 2.0 Array)   238941_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000327994
Ensembl peptide - ENSP00000413875
NCBI entrez gene - 135892     See in Manteia.
OMIM - 612548
RefSeq - XM_011515789
RefSeq - NM_001281450
RefSeq - NM_001281451
RefSeq - NM_178125
RefSeq - XM_011515787
RefSeq - XM_011515788
RefSeq Peptide - NP_001268379
RefSeq Peptide - NP_001268380
RefSeq Peptide - NP_835226
swissprot - Q2M204
swissprot - Q86XT4
Ensembl - ENSG00000146755
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000021696Gallus gallus
 Q810I2ENSMUSG00000053388Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q86UV7 / TRIM73 / tripartite motif containing 73ENSG0000017880948
Q86UV6 / TRIM74 / tripartite motif containing 74ENSG0000015542848
Q6ZMU5 / TRIM72 / tripartite motif containing 72ENSG0000017723832
TRIM7 / Q9C029 / tripartite motif containing 7ENSG0000014605429
P14373 / TRIM27 / tripartite motif containing 27ENSG0000020471326
Q8WV44 / TRIM41 / tripartite motif containing 41ENSG0000014606326
MEFV / O15553 / MEFV, pyrin innate immunity regulatorENSG0000010331325
Q9UPQ4 / TRIM35 / tripartite motif containing 35ENSG0000010422825
Q86WT6 / TRIM69 / tripartite motif containing 69ENSG0000018588025
Q9BVG3 / TRIM62 / tripartite motif containing 62ENSG0000011652525
Q9UDY6 / TRIM10 / tripartite motif containing 10ENSG0000020461325
Q12899 / TRIM26 / tripartite motif containing 26ENSG0000023412723
Q9C019 / TRIM15 / tripartite motif containing 15ENSG0000020461020
Q9BZY9 / TRIM31 / tripartite motif containing 31ENSG0000020461615
Q96A61 / TRIM52 / tripartite motif containing 52ENSG0000018371810


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR001870  B30.2/SPRY domain
 IPR003877  SPRY domain
 IPR003879  Butyrophylin-like, SPRY domain
 IPR006574  SPRY-associated
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027370  RING-type zinc-finger, LisH dimerisation motif


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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