ENSG00000116525


Homo sapiens

Features
Gene ID: ENSG00000116525
  
Biological name :TRIM62
  
Synonyms : Q9BVG3 / TRIM62 / tripartite motif containing 62
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p35.1
Gene start: 33145402
Gene end: 33182059
  
Corresponding Affymetrix probe sets: 219272_at (Human Genome U133 Plus 2.0 Array)   236845_at (Human Genome U133 Plus 2.0 Array)   58308_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000291416
Ensembl peptide - ENSP00000441173
NCBI entrez gene - 55223     See in Manteia.
OMIM - 616755
RefSeq - XM_017001630
RefSeq - NM_018207
RefSeq - XM_011541705
RefSeq - XM_017001629
RefSeq Peptide - NP_001317412
RefSeq Peptide - NP_060677
swissprot - Q9BVG3
Ensembl - ENSG00000116525
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-193i15.2ENSDARG00000095536Danio rerio
 trim62ENSDARG00000060901Danio rerio
 TRIM62ENSGALG00000028437Gallus gallus
 Q80V85ENSMUSG00000041000Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TRIM7 / Q9C029 / tripartite motif containing 7ENSG0000014605429
Q86WT6 / TRIM69 / tripartite motif containing 69ENSG0000018588029
P14373 / TRIM27 / tripartite motif containing 27ENSG0000020471328
Q8WV44 / TRIM41 / tripartite motif containing 41ENSG0000014606327
Q86XT4 / TRIM50 / tripartite motif containing 50ENSG0000014675526
Q9UPQ4 / TRIM35 / tripartite motif containing 35ENSG0000010422825
MEFV / O15553 / MEFV, pyrin innate immunity regulatorENSG0000010331325
Q12899 / TRIM26 / tripartite motif containing 26ENSG0000023412724
Q9UDY6 / TRIM10 / tripartite motif containing 10ENSG0000020461323
Q6ZMU5 / TRIM72 / tripartite motif containing 72ENSG0000017723823
Q9C019 / TRIM15 / tripartite motif containing 15ENSG0000020461022
Q9BZY9 / TRIM31 / tripartite motif containing 31ENSG0000020461615
Q86UV6 / TRIM74 / tripartite motif containing 74ENSG0000015542811
Q86UV7 / TRIM73 / tripartite motif containing 73ENSG0000017880911
Q96A61 / TRIM52 / tripartite motif containing 52ENSG0000018371811


Protein motifs (from Interpro)
Interpro ID Name
 IPR000315  B-box-type zinc finger
 IPR001841  Zinc finger, RING-type
 IPR001870  B30.2/SPRY domain
 IPR003877  SPRY domain
 IPR003879  Butyrophylin-like, SPRY domain
 IPR006574  SPRY-associated
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR013320  Concanavalin A-like lectin/glucanase domain superfamily
 IPR017907  Zinc finger, RING-type, conserved site
 IPR027267  AH/BAR domain superfamily
 IPR035830  TRIM62, PRY/SPRY domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010719 negative regulation of epithelial to mesenchymal transition IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032897 negative regulation of viral transcription IDA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0045087 innate immune response IMP
 biological_processGO:0046596 regulation of viral entry into host cell IDA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0060333 interferon-gamma-mediated signaling pathway TAS
 biological_processGO:1902186 regulation of viral release from host cell IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0004842 ubiquitin-protein transferase activity IDA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Interferon gamma signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr